Abstract
It stems from the magnetism: The extraction of stem/progenitor cells from the brain of live animals is possible using antibodies conjugated to magnetic nanoparticles (Ab-MNPs). The Ab-MNPs are introduced to a rat's brain with a superfine micro-syringe. The stem cells attach to the Ab-MNPs and are magnetically isolated and removed. They can develop into neurospheres and differentiate into different types of cells outside the subject body. The rat remains alive and healthy.
Original language | English |
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Pages (from-to) | 12298-12302 |
Number of pages | 5 |
Journal | Angewandte Chemie. International Edition |
Volume | 52 |
Issue number | 47 |
Early online date | 24 Sept 2013 |
DOIs | |
Publication status | Published - 18 Nov 2013 |
Scopus Subject Areas
- Catalysis
- Chemistry(all)
User-Defined Keywords
- antibodies
- magnetic nanoparticles
- nanoparticles
- regenerative medicine
- stem cells