Nano-functionalized long-period fiber grating probe for disease-specific protein detection

Deependra Tyagi; Satyendra Kumar Mishra; Bing Zou; Congcong Lin; Ting Hao; Ge  Zhang; Aiping  Lu; Kin Seng Chiang; Zhijun  Yang

doi:10.1039/c7tb02406a

Nano-functionalized long-period fiber grating probe for disease-specific protein detection

Deependra Tyagi
, Satyendra Kumar Mishra
, Bing Zou
, Congcong Lin
, Ting Hao
, Ge Zhang
, Aiping Lu^*
, Kin Seng Chiang^*
, Zhijun Yang^*

^*Corresponding author for this work

Research output: Contribution to journal › Journal article › peer-review

30 Citations (Scopus)

Abstract

Optical biosensors have great significance for rapid and sensitive detection and monitoring of biomolecular interactions. Here, recent advancement in the nano-functionalized long-period fiber grating (LPFG) is used to develop a cost-effective approach for label-free and real-time detection of the carbonic anhydrase-IX (CA9) monoclonal antibody, a diagnostic biomarker in hypoxia condition cultured carcinoma cells.

Original language	English
Pages (from-to)	386-392
Number of pages	7
Journal	Journal of Materials Chemistry B
Volume	6
Issue number	3
DOIs	https://doi.org/10.1039/c7tb02406a
Publication status	Published - 21 Jan 2018

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10.1039/c7tb02406a

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title = "Nano-functionalized long-period fiber grating probe for disease-specific protein detection",

abstract = "Optical biosensors have great significance for rapid and sensitive detection and monitoring of biomolecular interactions. Here, recent advancement in the nano-functionalized long-period fiber grating (LPFG) is used to develop a cost-effective approach for label-free and real-time detection of the carbonic anhydrase-IX (CA9) monoclonal antibody, a diagnostic biomarker in hypoxia condition cultured carcinoma cells.",

author = "Deependra Tyagi and Mishra, \{Satyendra Kumar\} and Bing Zou and Congcong Lin and Ting Hao and Ge Zhang and Aiping Lu and Chiang, \{Kin Seng\} and Zhijun Yang",

note = "Funding Information: We gratefully acknowledge funding for this work provided by the University Grants Committee of Hong Kong for the General Research Fund (GRF/RGC Ref. No. 12102514—HKBU: 32-14-125; CityU 11202014). D. Tyagi and S. K. Mishra contributed equally to this work. University Grants Committee (12102514, 32-14-125, 11202014) Publisher copyright: {\textcopyright} 2018 The Royal Society of Chemistry.",

year = "2018",

month = jan,

day = "21",

doi = "10.1039/c7tb02406a",

language = "English",

volume = "6",

pages = "386--392",

journal = "Journal of Materials Chemistry B",

issn = "2050-750X",

publisher = "Royal Society of Chemistry",

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TY - JOUR

T1 - Nano-functionalized long-period fiber grating probe for disease-specific protein detection

AU - Tyagi, Deependra

AU - Mishra, Satyendra Kumar

AU - Zou, Bing

AU - Lin, Congcong

AU - Hao, Ting

AU - Zhang, Ge

AU - Lu, Aiping

AU - Chiang, Kin Seng

AU - Yang, Zhijun

N1 - Funding Information: We gratefully acknowledge funding for this work provided by the University Grants Committee of Hong Kong for the General Research Fund (GRF/RGC Ref. No. 12102514—HKBU: 32-14-125; CityU 11202014). D. Tyagi and S. K. Mishra contributed equally to this work. University Grants Committee (12102514, 32-14-125, 11202014) Publisher copyright: © 2018 The Royal Society of Chemistry.

PY - 2018/1/21

Y1 - 2018/1/21

N2 - Optical biosensors have great significance for rapid and sensitive detection and monitoring of biomolecular interactions. Here, recent advancement in the nano-functionalized long-period fiber grating (LPFG) is used to develop a cost-effective approach for label-free and real-time detection of the carbonic anhydrase-IX (CA9) monoclonal antibody, a diagnostic biomarker in hypoxia condition cultured carcinoma cells.

AB - Optical biosensors have great significance for rapid and sensitive detection and monitoring of biomolecular interactions. Here, recent advancement in the nano-functionalized long-period fiber grating (LPFG) is used to develop a cost-effective approach for label-free and real-time detection of the carbonic anhydrase-IX (CA9) monoclonal antibody, a diagnostic biomarker in hypoxia condition cultured carcinoma cells.

UR - https://www.scopus.com/pages/publications/85040863734

U2 - 10.1039/c7tb02406a

DO - 10.1039/c7tb02406a

M3 - Journal article

C2 - 32254518

AN - SCOPUS:85040863734

SN - 2050-750X

VL - 6

SP - 386

EP - 392

JO - Journal of Materials Chemistry B

JF - Journal of Materials Chemistry B

IS - 3

ER -

Nano-functionalized long-period fiber grating probe for disease-specific protein detection

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