Nano-functionalized long-period fiber grating probe for disease-specific protein detection

Deependra Tyagi, Satyendra Kumar Mishra, Bing Zou, Congcong Lin, Ting Hao, Ge Zhang, Aiping Lu*, Kin Seng Chiang*, Zhijun Yang*

*Corresponding author for this work

Research output: Contribution to journalJournal articlepeer-review

21 Citations (Scopus)


Optical biosensors have great significance for rapid and sensitive detection and monitoring of biomolecular interactions. Here, recent advancement in the nano-functionalized long-period fiber grating (LPFG) is used to develop a cost-effective approach for label-free and real-time detection of the carbonic anhydrase-IX (CA9) monoclonal antibody, a diagnostic biomarker in hypoxia condition cultured carcinoma cells.

Original languageEnglish
Pages (from-to)386-392
Number of pages7
JournalJournal of Materials Chemistry B
Issue number3
Publication statusPublished - 21 Jan 2018

Scopus Subject Areas

  • Chemistry(all)
  • Biomedical Engineering
  • Materials Science(all)


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