MOST: Most-similar ligand based approach to target prediction

Keyphrases

• Bioactivity 100%
• Ligand-based Approaches 100%
• Target Prediction 100%
• Morgan Fingerprint 42%
• Logistic Regression 42%
• Action Targets 28%
• False Discovery Rate Control 28%
• Control Method 28%
• Similarity Search 28%
• Chemical Similarity 28%
• Multi-target 28%
• Mechanism of Action 28%
• Nave Bayes 14%
• Acetylcholinesterase 14%
• Training Model 14%
• Regression Forest 14%
• Drug Repurposing 14%
• Temporal Validation 14%
• Machine Learning Techniques 14%
• Computational Approach 14%
• Prediction Power 14%
• Reverse Docking 14%
• Laxative Effect 14%
• Prediction Accuracy 14%
• Bioactivity Data 14%
• Robust Index 14%
• Fingerprint Matching 14%
• Ligand-based 14%
• Inference Approach 14%
• Drug Mechanism 14%
• Prediction Scenarios 14%
• Random Forest Method 14%
• ChEMBL 14%
• Human Target 14%
• Machine Learning 14%
• Spectral Analysis 14%
• Highly Accurate 14%
• Aloe-emodin 14%

Agricultural and Biological Sciences

• Fingerprint 100%
• in Vivo Studies 20%
• Aloe 20%
• Acetylcholinesterase 20%