TY - JOUR
T1 - Monoterpene derivatives from the roots of Paeonia lactiflora and their anti-proliferative activity
AU - Li, Pan
AU - Zhang, Ze Ming
AU - Li, Tao
AU - Zhang, Yan-Bo
AU - Sze, Stephen Cho Wing
AU - Wang, Guo Cai
AU - Li, Yao Lan
AU - Ye, Wencai
PY - 2014/10
Y1 - 2014/10
N2 - An unusual nor-monoterpene with only nine carbons, nor-paeonilactone (1), two new monoterpenes, paeonisuffrone C (2), paeonilactone D (9), and a new monoterpene glucoside, paeonin D (3), along with ten known compounds were isolated from the dried roots of Paeonia lactiflora. Their structures were elucidated on the basis of spectroscopic analysis, including 1D and 2D NMR, and computational data. Compounds 4–14 were evaluated for their anti-proliferative activities against BT 483 human breast cancer cells and OVCA 429 human ovarian cancer cells by MTT assay.
AB - An unusual nor-monoterpene with only nine carbons, nor-paeonilactone (1), two new monoterpenes, paeonisuffrone C (2), paeonilactone D (9), and a new monoterpene glucoside, paeonin D (3), along with ten known compounds were isolated from the dried roots of Paeonia lactiflora. Their structures were elucidated on the basis of spectroscopic analysis, including 1D and 2D NMR, and computational data. Compounds 4–14 were evaluated for their anti-proliferative activities against BT 483 human breast cancer cells and OVCA 429 human ovarian cancer cells by MTT assay.
KW - Paeonia lactiflora
KW - Paeoniaceae
KW - Monoterpene
KW - Anti-proliferative
UR - http://www.scopus.com/inward/record.url?eid=2-s2.0-84907363650&partnerID=MN8TOARS
U2 - 10.1016/j.fitote.2014.07.017
DO - 10.1016/j.fitote.2014.07.017
M3 - Journal article
SN - 0367-326X
VL - 98
SP - 124
EP - 129
JO - Fitoterapia
JF - Fitoterapia
ER -
