@article{0f3b811a5ca1461a8258eadcdccccc82,
title = "Mimicking strategy for protein-protein interaction inhibitor discovery by virtual screening",
abstract = "As protein-protein interactions (PPIs) are highly involved in most cellular processes, the discovery of PPI inhibitors that mimic the structure of the natural protein partners is a promising strategy toward the discovery of PPI inhibitors. In this review, we discuss recent advances in the application of virtual screening for identifying mimics of protein partners. The classification and function of the mimicking protein partner inhibitor discovery by virtual screening are described. We anticipate that this review would be of interest to medicinal chemists and chemical biologists working in the field of protein-protein interaction inhibitors or probes.",
keywords = "Drug discovery, Mimetics, Protein-protein interactions, Virtual screening",
author = "Wu, {Ke Jia} and Lei, {Pui Man} and Hao Liu and Chun Wu and Leung, {Chung Hang} and Ma, {Dik Lung}",
note = "Funding Information: Funding: This research was funded by the Hong Kong Baptist University (FRG2/17-18/003), the Health and Medical Research Fund (HMRF/14150561), the National Natural Science Foundation of China (201575121and 21775131, China), the Hong Kong Baptist University Century Club Sponsorship Scheme 2018 (China), the Interdisciplinary Research Matching Scheme (RC-IRMS/16-17/03, China), the Interdisciplinary Research Clusters Matching Scheme (RC-IRCs/17-18/03, China), the Collaborative Research Fund (C5026-16G, China), the SKLEBA and HKBU Strategic Development Fund (SKLP_1718_P04, China), the Science and Technology Development Fund, the Macau SAR (File no. 0072/2018/A2 and SKL-QRCM-2017-2019), and the University of Macau (MYRG2018-00187-ICMS, China).",
year = "2019",
month = dec,
day = "4",
doi = "10.3390/molecules24244428",
language = "English",
volume = "24",
journal = "Molecules",
issn = "1420-3049",
publisher = "MDPI",
number = "24",
}