TY - JOUR
T1 - Microfluidics for Combating Antimicrobial Resistance
AU - Liu, Zhengzhi
AU - Banaei, Niaz
AU - Ren, Kangning
N1 - Funding Information:
This work was supported by Hong Kong Baptist University ( FRG2/15-16/002 , FRG2/16-17/062 , SDF 03-17-096), Hong Kong RGC ( 22200515 ), and the National Natural Science Foundation of China ( 21575121 ).
PY - 2017/12
Y1 - 2017/12
N2 - The ever-growing threat of antimicrobial resistance (AMR) demands
immediate countermeasures. With its novelty and enabling features
including downscaled analysis, precisely controlled local environment,
and enhanced speed, accuracy, and cost-efficiency, microfluidics has
demonstrated potential in several key areas, including furthering our
understanding of bacteria, developing better susceptibility testing
tools, and overcoming obstacles in discovery and research of new
antibiotics. While ample research results in the field of microfluidics
are available, their transformation into practical application is still
lagging far behind. We believe that the challenge of AMR will give
microfluidics a much-needed opportunity to leap from research papers to
true productivity, and gain wider acceptance as a mature technology.
AB - The ever-growing threat of antimicrobial resistance (AMR) demands
immediate countermeasures. With its novelty and enabling features
including downscaled analysis, precisely controlled local environment,
and enhanced speed, accuracy, and cost-efficiency, microfluidics has
demonstrated potential in several key areas, including furthering our
understanding of bacteria, developing better susceptibility testing
tools, and overcoming obstacles in discovery and research of new
antibiotics. While ample research results in the field of microfluidics
are available, their transformation into practical application is still
lagging far behind. We believe that the challenge of AMR will give
microfluidics a much-needed opportunity to leap from research papers to
true productivity, and gain wider acceptance as a mature technology.
KW - antimicrobial resistance
KW - antimicrobial susceptibility testing
KW - drug discovery
KW - microfluidics
UR - http://www.scopus.com/inward/record.url?scp=85033670876&partnerID=8YFLogxK
U2 - 10.1016/j.tibtech.2017.07.008
DO - 10.1016/j.tibtech.2017.07.008
M3 - Review article
C2 - 29153761
AN - SCOPUS:85033670876
SN - 0167-7799
VL - 35
SP - 1129
EP - 1139
JO - Trends in Biotechnology
JF - Trends in Biotechnology
IS - 12
ER -