Methylene violet 3RAX-conjugated porphyrin for photodynamic therapy: Synthesis, DNA photocleavage, and cell study

Si Yao, Yunman Zheng, Lijun Jiang, Chen Xie, Fengshou Wu*, Chi Huang, Xiong Zhang, Ka-Leung WONG, Zaoying Li, Kai Wang

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

17 Citations (Scopus)

Abstract

A methylene violet 3RAX-conjugated porphyrin has been designed and synthesized as a potential photosensitizer in photodynamic therapy because of its high DNA binding constant and the efficacy in inhibiting cancer cells with subcellular localization.

Original languageEnglish
Pages (from-to)4472-4477
Number of pages6
JournalRSC Advances
Volume8
Issue number8
DOIs
Publication statusPublished - 2018

Scopus Subject Areas

  • Chemistry(all)
  • Chemical Engineering(all)

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