TY - JOUR
T1 - Metabolic engineering approaches for scale-up of fermentative biohydrogen production–A review
AU - Akaniro, Ifunanya Rejoice
AU - Oladipo, Akeem Adeyemi
AU - Onwujekwe, Emmanuel Chijioke
N1 - Publisher Copyright:
© 2023 Hydrogen Energy Publications LLC
PY - 2024/1/2
Y1 - 2024/1/2
N2 - Significant efforts are being made to produce biofuels to replace fossil fuels and address the issues caused by global climate change. Due to its potential better conversion efficiency to useable power, decreased emission of pollutants, and high energy density, H2 is one of the prospective options that are seen as a desirable future clean energy carrier. Although there are numerous technologies available for producing H2, this review concentrates on fermentative H2 production techniques, their drawbacks, and current developments. While being a promising method, fermentative strategies still have several drawbacks, including low H2 production yields. Many approaches have been used to address these issues; among them, the field of metabolic pathway engineering has made enormous strides. To improve H2 generation, this paper reviewed and discussed several metabolic pathways and modified strains. As well as the challenges involved in H2 scale-up from a laboratory setting to a commercial scale.
AB - Significant efforts are being made to produce biofuels to replace fossil fuels and address the issues caused by global climate change. Due to its potential better conversion efficiency to useable power, decreased emission of pollutants, and high energy density, H2 is one of the prospective options that are seen as a desirable future clean energy carrier. Although there are numerous technologies available for producing H2, this review concentrates on fermentative H2 production techniques, their drawbacks, and current developments. While being a promising method, fermentative strategies still have several drawbacks, including low H2 production yields. Many approaches have been used to address these issues; among them, the field of metabolic pathway engineering has made enormous strides. To improve H2 generation, this paper reviewed and discussed several metabolic pathways and modified strains. As well as the challenges involved in H2 scale-up from a laboratory setting to a commercial scale.
KW - Biofuel
KW - Dark fermentation
KW - Hydrogen energy
KW - Hydrogen-producing enzymes
KW - Metabolically engineered strains
UR - http://www.scopus.com/inward/record.url?scp=85159285088&partnerID=8YFLogxK
U2 - 10.1016/j.ijhydene.2023.04.328
DO - 10.1016/j.ijhydene.2023.04.328
M3 - Journal article
SN - 0360-3199
VL - 52, Part D
SP - 240
EP - 264
JO - International Journal of Hydrogen Energy
JF - International Journal of Hydrogen Energy
ER -
