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Luminescent Ruthenium(II) Complex Bearing Bipyridine and N-Heterocyclic Carbene-based C∧N∧C Pincer Ligand for Live-Cell Imaging of Endocytosis

  • Wai Kuen Tsui
  • , Lai Hon Chung
  • , Matthew Man Kin Wong
  • , Wai Him Tsang
  • , Hoi Shing Lo
  • , Yaxiang Liu
  • , Chung Hang Leung
  • , Dik Lung Ma
  • , Sung Kay Chiu*
  • , Chun Yuen Wong
  • *Corresponding author for this work

Research output: Contribution to journalJournal articlepeer-review

26 Citations (Scopus)

Abstract

Luminescent ruthenium(II)-cyanide complex with N-heterocyclic carbene pincer ligand C∧N∧C = 2,6-bis(1-butylimidazol-2-ylidene)pyridine and 2,2′-bipyridine (bpy) shows minimal cytotoxicity to both human breast carcinoma cell (MCF-7) and human retinal pigmented epithelium cell (RPE) in a wide range of concentration (0.1-500 μM), and can be used for the luminescent imaging of endocytosis of the complex in these cells.

Original languageEnglish
Article number9070
JournalScientific Reports
Volume5
DOIs
Publication statusPublished - 13 Mar 2015

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

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