Luminescent Ruthenium(II) Complex Bearing Bipyridine and N-Heterocyclic Carbene-based C∧N∧C Pincer Ligand for Live-Cell Imaging of Endocytosis

Wai Kuen Tsui, Lai Hon Chung, Matthew Man Kin Wong, Wai Him Tsang, Hoi Shing Lo, Yaxiang Liu, Chung Hang Leung, Edmond Dik Lung MA, Sung Kay Chiu*, Chun Yuen Wong

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

15 Citations (Scopus)

Abstract

Luminescent ruthenium(II)-cyanide complex with N-heterocyclic carbene pincer ligand C∧N∧C = 2,6-bis(1-butylimidazol-2-ylidene)pyridine and 2,2′-bipyridine (bpy) shows minimal cytotoxicity to both human breast carcinoma cell (MCF-7) and human retinal pigmented epithelium cell (RPE) in a wide range of concentration (0.1-500 μM), and can be used for the luminescent imaging of endocytosis of the complex in these cells.

Original languageEnglish
Article number9070
JournalScientific Reports
Volume5
DOIs
Publication statusPublished - 13 Mar 2015

Scopus Subject Areas

  • General

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