Luminescent G-quadruplex probes

Dik Lung Ma; Daniel Shiu Hin Chan; Hui Yang; Hong Zhang He; Chung Hang Leung

doi:10.2174/138161212799958314

Luminescent G-quadruplex probes

Dik Lung Ma
, Daniel Shiu Hin Chan
, Hui Yang
, Hong Zhang He
, Chung Hang Leung

Department of Chemistry

Research output: Contribution to journal › Review article › peer-review

45 Citations (Scopus)

Abstract

G-quadruplexes have found increasing potential in applications such as molecular therapeutics, diagnostics, and sensing. As a consequence, small molecules capable of selectively detecting G-quadruplexes have received significant attention in recent literature. Our review here addresses representative advances in the development of luminescent G-quadruplex probes and highlights their potential applications in sensing and imaging.

Original language	English
Pages (from-to)	2058-2075
Number of pages	18
Journal	Current Pharmaceutical Design
Volume	18
Issue number	14
DOIs	https://doi.org/10.2174/138161212799958314
Publication status	Published - May 2012

User-Defined Keywords

Detection
DNA
G-quadruplex
Luminescent probes
Small molecules

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10.2174/138161212799958314

Cite this

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title = "Luminescent G-quadruplex probes",

abstract = "G-quadruplexes have found increasing potential in applications such as molecular therapeutics, diagnostics, and sensing. As a consequence, small molecules capable of selectively detecting G-quadruplexes have received significant attention in recent literature. Our review here addresses representative advances in the development of luminescent G-quadruplex probes and highlights their potential applications in sensing and imaging.",

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year = "2012",

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AU - Ma, Dik Lung

AU - Chan, Daniel Shiu Hin

AU - Yang, Hui

AU - He, Hong Zhang

AU - Leung, Chung Hang

PY - 2012/5

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N2 - G-quadruplexes have found increasing potential in applications such as molecular therapeutics, diagnostics, and sensing. As a consequence, small molecules capable of selectively detecting G-quadruplexes have received significant attention in recent literature. Our review here addresses representative advances in the development of luminescent G-quadruplex probes and highlights their potential applications in sensing and imaging.

AB - G-quadruplexes have found increasing potential in applications such as molecular therapeutics, diagnostics, and sensing. As a consequence, small molecules capable of selectively detecting G-quadruplexes have received significant attention in recent literature. Our review here addresses representative advances in the development of luminescent G-quadruplex probes and highlights their potential applications in sensing and imaging.

KW - Detection

KW - DNA

KW - G-quadruplex

KW - Luminescent probes

KW - Small molecules

UR - https://www.scopus.com/pages/publications/84860131858

U2 - 10.2174/138161212799958314

DO - 10.2174/138161212799958314

M3 - Review article

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VL - 18

SP - 2058

EP - 2075

JO - Current Pharmaceutical Design

JF - Current Pharmaceutical Design

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ER -

Luminescent G-quadruplex probes

Abstract

User-Defined Keywords

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