Luminescent G-quadruplex probes

Edmond Dik Lung MA, Daniel Shiu Hin Chan, Hui Yang, Hong Zhang He, Chung Hang Leung

Research output: Contribution to journalReview articlepeer-review

41 Citations (Scopus)

Abstract

G-quadruplexes have found increasing potential in applications such as molecular therapeutics, diagnostics, and sensing. As a consequence, small molecules capable of selectively detecting G-quadruplexes have received significant attention in recent literature. Our review here addresses representative advances in the development of luminescent G-quadruplex probes and highlights their potential applications in sensing and imaging.

Original languageEnglish
Pages (from-to)2058-2075
Number of pages18
JournalCurrent Pharmaceutical Design
Volume18
Issue number14
DOIs
Publication statusPublished - May 2012

Scopus Subject Areas

  • Pharmacology
  • Drug Discovery

User-Defined Keywords

  • Detection
  • DNA
  • G-quadruplex
  • Luminescent probes
  • Small molecules

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