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Linear-Time Haplotype Inference on Pedigrees Without Recombinations

  • M. Y. Chan*
  • , Wun Tat Chan
  • , Francis Y.L. Chin
  • , Stanley P.Y. Fung
  • , Ming Yang Kao
  • *Corresponding author for this work

Research output: Chapter in book/report/conference proceedingConference proceedingpeer-review

18 Citations (Scopus)

Abstract

In this paper, a linear-time algorithm, which is optimal, is presented to solve the haplotype inference problem for pedigree data when there are no recombinations and the pedigree has no mating loops. The approach is based on the use of graphs to capture SNP, Mendelian and parity constraints of the given pedigree.

Original languageEnglish
Title of host publicationAlgorithms in Bioinformatics
Subtitle of host publication6th International Workshop, WABI 2006, Zurich, Switzerland, September 11-13, 2006, Proceedings
EditorsPhilipp Bücher, Bernard M. E. Moret
Place of PublicationHeidelberg
PublisherSpringer Berlin Heidelberg
Pages56-67
Number of pages12
Edition1st
ISBN (Electronic)9783540395843
ISBN (Print)3540395830, 9783540395836
DOIs
Publication statusPublished - 30 Aug 2006
Event6th International Workshop on Algorithms in Bioinformatics, WABI 2006 - Zurich, Switzerland
Duration: 11 Sept 200613 Sept 2006

Publication series

NameLecture Notes in Computer Science
Volume4175
ISSN (Print)0302-9743
ISSN (Electronic)1611-3349
NameLecture Notes in Bioinformatics
ISSN (Print)2366-6323
ISSN (Electronic)2366-6331
NameWABI: International Workshop on Algorithms in Bioinformatics

Conference

Conference6th International Workshop on Algorithms in Bioinformatics, WABI 2006
Country/TerritorySwitzerland
CityZurich
Period11/09/0613/09/06

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 9 - Industry, Innovation, and Infrastructure
    SDG 9 Industry, Innovation, and Infrastructure

User-Defined Keywords

  • Family Problem
  • Pedigree Data
  • Heterozygous Locus
  • Haplotype Inference
  • Haplotype Pair

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