TY - JOUR
T1 - Ligands derived from C-aryl substituted derivatives of cyclen
T2 - Formation of kinetically unstable complexes with lanthanide(III) ions
AU - Edlin, Christopher D.
AU - Faulkner, Stephen
AU - Parker, David
AU - Wilkinson, Matthew P.
AU - Woods, Mark
AU - Lin, Jin
AU - Lasri, Elisabeth
AU - Neth, Françoise
AU - Port, Marc
PY - 1998/12
Y1 - 1998/12
N2 - The synthesis of C-aryl monosubstituted derivatives of 1,4,7,10-tetraazacyclododecane (cyclen) by metal templated reductive amination of triethylenetetramine with aryl glyoxals has been developed and shown to be widely applicable. Octadentate ligands derived from these C-substituted macrocycles form relatively labile eight-coordinate complexes, which dissociate when challenged with EDTA in aqueous solution at pH 5.5, suggesting their use in metal-transport processes rather than for applications in vivo.
AB - The synthesis of C-aryl monosubstituted derivatives of 1,4,7,10-tetraazacyclododecane (cyclen) by metal templated reductive amination of triethylenetetramine with aryl glyoxals has been developed and shown to be widely applicable. Octadentate ligands derived from these C-substituted macrocycles form relatively labile eight-coordinate complexes, which dissociate when challenged with EDTA in aqueous solution at pH 5.5, suggesting their use in metal-transport processes rather than for applications in vivo.
UR - https://www.scopus.com/pages/publications/0011582720
U2 - 10.1039/a805231j
DO - 10.1039/a805231j
M3 - Journal article
AN - SCOPUS:0011582720
SN - 1144-0546
VL - 22
SP - 1359
EP - 1364
JO - New Journal of Chemistry
JF - New Journal of Chemistry
IS - 12
ER -
