Abstract
Lanthanide complex-based medicine combining organic ligands and individual lanthanide ions is proving successful in therapeutics, especially in drug delivery, chemotherapy, and photodynamic therapy. In this review, I discuss the coordination chemistry, antenna effect, and chelating ligands of lanthanide complexes and their key features benefiting the therapeutical monitoring and performance, such as fingerprint emissions, large pseudo-Stokes’ shifts, long lifetimes, two-photon excitations and magnetic resonance responses. While illustrating their pharmaceutical applications in drug delivery, chemotherapy and photodynamic therapy, I identify the challenges and prospective opportunities in clinical translation of the lanthanide complex-based medicine.
| Original language | English |
|---|---|
| Article number | 117622 |
| Journal | Journal of Luminescence |
| Volume | 228 |
| DOIs | |
| Publication status | Published - Dec 2020 |
UN SDGs
This output contributes to the following UN Sustainable Development Goals (SDGs)
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SDG 9 Industry, Innovation, and Infrastructure
User-Defined Keywords
- Chemotherapy
- Drug delivery
- Lanthanide complex
- Photodynamic therapy
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