Label-free sensing of pH and silver nanoparticles using an OR logic gate

Edmond Dik Lung MA; Hong Zhang He; Victor Pui Yan Ma; Daniel Shiu Hin Chan; Ka Ho Leung; Hai Jing Zhong; Lihua Lu; Jean Louis Mergny; Chung Hang Leung

doi:10.1016/j.aca.2012.04.041

Label-free sensing of pH and silver nanoparticles using an OR logic gate

Edmond Dik Lung MA^*, Hong Zhang He, Victor Pui Yan Ma, Daniel Shiu Hin Chan, Ka Ho Leung, Hai Jing Zhong, Lihua Lu, Jean Louis Mergny, Chung Hang Leung

^*Corresponding author for this work

Department of Chemistry

Research output: Contribution to journal › Journal article › peer-review

30 Citations (Scopus)

Abstract

Many natural phenomena are associated with the presence of two or more separate variables. We report here an "OR" DNA logic gate based on a luminescent platinum(II) switch-on probe for silver nanoparticles and pH, both of which may be considered putative indicators of pollution. The modulation of metal complex/double-stranded DNA complex phosphorescence by Ag⁺ and H⁺ was used to construct a simple, rapid and label-free method for the label-free detection of pH and nanomolar Ag⁺ ions and nanoparticles in aqueous solutions with high selectivity.

Original language	English
Pages (from-to)	78-83
Number of pages	6
Journal	Analytica Chimica Acta
Volume	733
DOIs	https://doi.org/10.1016/j.aca.2012.04.041
Publication status	Published - 6 Jul 2012

Scopus Subject Areas

Analytical Chemistry
Biochemistry
Environmental Chemistry
Spectroscopy

User-Defined Keywords

Label-free detection
Logic gate
Luminescent probe
Platinum(II) complex
Silver nanoparticle

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10.1016/j.aca.2012.04.041

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title = "Label-free sensing of pH and silver nanoparticles using an OR logic gate",

abstract = "Many natural phenomena are associated with the presence of two or more separate variables. We report here an {"}OR{"} DNA logic gate based on a luminescent platinum(II) switch-on probe for silver nanoparticles and pH, both of which may be considered putative indicators of pollution. The modulation of metal complex/double-stranded DNA complex phosphorescence by Ag+ and H+ was used to construct a simple, rapid and label-free method for the label-free detection of pH and nanomolar Ag+ ions and nanoparticles in aqueous solutions with high selectivity.",

keywords = "Label-free detection, Logic gate, Luminescent probe, Platinum(II) complex, Silver nanoparticle",

author = "MA, {Edmond Dik Lung} and He, {Hong Zhang} and Ma, {Victor Pui Yan} and Chan, {Daniel Shiu Hin} and Leung, {Ka Ho} and Zhong, {Hai Jing} and Lihua Lu and Mergny, {Jean Louis} and Leung, {Chung Hang}",

note = "Funding Information: This work is supported by Hong Kong Baptist University (FRG2/10-11/008 and FRG2/11-12/009), Environment and Conservation Fund (ECF Project 3/2010), Centre for Cancer and Inflammation Research, School of Chinese Medicine (CCIR-SCM, HKBU), the Research Fund for the Control of Infectious Diseases (RFCID/11101212), the Research Grants Council (HKBU/201811) and the University of Macau (Start-up Research Grant to C.-H. Leung). ",

year = "2012",

month = jul,

day = "6",

doi = "10.1016/j.aca.2012.04.041",

language = "English",

volume = "733",

pages = "78--83",

journal = "Analytica Chimica Acta",

issn = "0003-2670",

publisher = "Elsevier",

}

TY - JOUR

T1 - Label-free sensing of pH and silver nanoparticles using an OR logic gate

AU - MA, Edmond Dik Lung

AU - He, Hong Zhang

AU - Ma, Victor Pui Yan

AU - Chan, Daniel Shiu Hin

AU - Leung, Ka Ho

AU - Zhong, Hai Jing

AU - Lu, Lihua

AU - Mergny, Jean Louis

AU - Leung, Chung Hang

N1 - Funding Information: This work is supported by Hong Kong Baptist University (FRG2/10-11/008 and FRG2/11-12/009), Environment and Conservation Fund (ECF Project 3/2010), Centre for Cancer and Inflammation Research, School of Chinese Medicine (CCIR-SCM, HKBU), the Research Fund for the Control of Infectious Diseases (RFCID/11101212), the Research Grants Council (HKBU/201811) and the University of Macau (Start-up Research Grant to C.-H. Leung).

PY - 2012/7/6

Y1 - 2012/7/6

N2 - Many natural phenomena are associated with the presence of two or more separate variables. We report here an "OR" DNA logic gate based on a luminescent platinum(II) switch-on probe for silver nanoparticles and pH, both of which may be considered putative indicators of pollution. The modulation of metal complex/double-stranded DNA complex phosphorescence by Ag+ and H+ was used to construct a simple, rapid and label-free method for the label-free detection of pH and nanomolar Ag+ ions and nanoparticles in aqueous solutions with high selectivity.

AB - Many natural phenomena are associated with the presence of two or more separate variables. We report here an "OR" DNA logic gate based on a luminescent platinum(II) switch-on probe for silver nanoparticles and pH, both of which may be considered putative indicators of pollution. The modulation of metal complex/double-stranded DNA complex phosphorescence by Ag+ and H+ was used to construct a simple, rapid and label-free method for the label-free detection of pH and nanomolar Ag+ ions and nanoparticles in aqueous solutions with high selectivity.

KW - Label-free detection

KW - Logic gate

KW - Luminescent probe

KW - Platinum(II) complex

KW - Silver nanoparticle

UR - http://www.scopus.com/inward/record.url?scp=84862491556&partnerID=8YFLogxK

U2 - 10.1016/j.aca.2012.04.041

DO - 10.1016/j.aca.2012.04.041

M3 - Journal article

C2 - 22704379

AN - SCOPUS:84862491556

SN - 0003-2670

VL - 733

SP - 78

EP - 83

JO - Analytica Chimica Acta

JF - Analytica Chimica Acta

ER -

Label-free sensing of pH and silver nanoparticles using an OR logic gate

Abstract

Scopus Subject Areas

User-Defined Keywords

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