@article{95e5d565b2694281836d0283d911162c,
title = "Iridium(III) complexes with 1,10-phenanthroline-based N^N ligands as highly selective luminescent G-quadruplex probes and application for switch-on ribonuclease H detection",
abstract = "A systematic study was performed to investigate the relationship between molecular structure and G-quadruplex sensing ability for a series of structurally related cyclometallated iridium(iii) complexes. The novel complex 7 was used to construct a label-free luminescent switch-on G-quadruplex-based assay for RNase H activity in buffered solution. The constructed detection platform was simple, low-cost and highly sensitive for RNase H, and functioned effectively in the presence of cellular debris.",
author = "Lihua Lu and Wanhe Wang and Chao Yang and Kang, {Tian Shu} and Leung, {Chung Hang} and Ma, {Edmond Dik Lung}",
note = "Funding Information: This work is supported by Research Foundation for Distinguished Scholars of Qingdao Agricultural University (663-1116010), Hong Kong Baptist University (FRG2/15-16/002), the Health and Medical Research Fund (HMRF/14130522), the Research Grants Council (HKBU/12301115, HKBU/204612 and HKBU/201913), the French Agence Nationale de la Recherche/Research Grants Council Joint Research Scheme (AHKBU201/12; Oligoswitch ANR-12-IS07-0001), the National Natural Science Foundation of China (21575121), the Guangdong Province Natural Science Foundation (2015A030313816), the Hong Kong Baptist University Century Club Sponsorship Scheme 2016, the Science and Technology Development Fund, Macao SAR (098/2014/A2), and the University of Macau (MYRG2015-00137-ICMS-QRCM and MRG044/LCH/2015/ICMS).",
year = "2016",
month = nov,
day = "14",
doi = "10.1039/c6tb02316a",
language = "English",
volume = "4",
pages = "6791--6796",
journal = "Journal of Materials Chemistry B",
issn = "2050-750X",
publisher = "Royal Society of Chemistry",
number = "42",
}