@article{dc48db76254d4a61b206549c2893b360,
title = "Iridium(III) Complexes Targeting Apoptotic Cell Death in Cancer Cells",
abstract = "Targeting apoptosis is a principal strategy in the design of anticancer drugs. In recent years, non-platinum-based scaffolds have been exploited as viable candidates for the exploitation of anticancer agents with potentially lower toxicity than the widely used cisplatin analogues. This review highlights the latest advances in developing iridium(III) complexes as anticancer agents that act particularly via targeting apoptotic cell death in cancer cells.",
keywords = "apoptosis, cancer, iridium(III) complex, mitochondria",
author = "Ma, {Edmond Dik Lung} and Chun Wu and Wu, {Ke Jia} and Leung, {Chung Hang}",
note = "Funding information: This research was funded by Hong Kong Baptist University (FRG2/17-18/003), the Health and Medical Research Fund (HMRF/14150561), the National Natural Science Foundation of China (21575121, 21775131 and 21762018), the Hong Kong Baptist University Century Club Sponsorship Scheme 2018, the Interdisciplinary Research Matching Scheme (RC-IRMS/16-17/03), the Interdisciplinary Research Clusters Matching Scheme (RC-IRCs/ 17-18/03), the Collaborative Research Fund (C5026-16G), the SKLEBA and HKBU Strategic Development Fund (SKLP_1718_P04), the Funded by The Science and Technology Development Fund, Macau SAR (File no. 0072/2018/A2), and the University of Macau (MYRG2016-00151-ICMS-QRCM and MYRG2018-00187-ICMS). ",
year = "2019",
month = jul,
day = "28",
doi = "10.3390/molecules24152739",
language = "English",
volume = "24",
journal = "Molecules",
issn = "1420-3049",
publisher = "MDPI",
number = "15",
}
