Iridium/copper-cocatalyzed asymmetric ring opening reaction of azabenzonorbornadienes with amines

Chaoyuan Zeng; Fan Yang; Jingchao Chen; Jun Wang; Baomin Fan

doi:10.1039/c5ob01243k

Iridium/copper-cocatalyzed asymmetric ring opening reaction of azabenzonorbornadienes with amines

Chaoyuan Zeng
, Fan Yang
, Jingchao Chen
, Jun Wang^*
, Baomin Fan^*

^*Corresponding author for this work

Department of Chemistry

Research output: Contribution to journal › Journal article › peer-review

36 Citations (Scopus)

Abstract

A combination of iridium/copper associated with (R)-Difluorphos catalyst for the asymmetric ring opening reaction of azabenzonorbornadienes with amines was developed, which afforded chiral trans-vicinal diamines in 80–97% yields with 93–95% enantioselectivities.

Original language	English
Pages (from-to)	8425-8428
Number of pages	4
Journal	Organic and Biomolecular Chemistry
Volume	13
Issue number	31
DOIs	https://doi.org/10.1039/c5ob01243k
Publication status	Published - 21 Aug 2015

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title = "Iridium/copper-cocatalyzed asymmetric ring opening reaction of azabenzonorbornadienes with amines",

abstract = "A combination of iridium/copper associated with (R)-Difluorphos catalyst for the asymmetric ring opening reaction of azabenzonorbornadienes with amines was developed, which afforded chiral trans-vicinal diamines in 80–97\% yields with 93–95\% enantioselectivities. ",

author = "Chaoyuan Zeng and Fan Yang and Jingchao Chen and Jun Wang and Baomin Fan",

note = "We gratefully thank the National Natural Science Foundation of China (NSFC 21402081, 21362043, 21302162) for financial support.",

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doi = "10.1039/c5ob01243k",

language = "English",

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journal = "Organic and Biomolecular Chemistry",

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T1 - Iridium/copper-cocatalyzed asymmetric ring opening reaction of azabenzonorbornadienes with amines

AU - Zeng, Chaoyuan

AU - Yang, Fan

AU - Chen, Jingchao

AU - Wang, Jun

AU - Fan, Baomin

N1 - We gratefully thank the National Natural Science Foundation of China (NSFC 21402081, 21362043, 21302162) for financial support.

PY - 2015/8/21

Y1 - 2015/8/21

N2 - A combination of iridium/copper associated with (R)-Difluorphos catalyst for the asymmetric ring opening reaction of azabenzonorbornadienes with amines was developed, which afforded chiral trans-vicinal diamines in 80–97% yields with 93–95% enantioselectivities.

AB - A combination of iridium/copper associated with (R)-Difluorphos catalyst for the asymmetric ring opening reaction of azabenzonorbornadienes with amines was developed, which afforded chiral trans-vicinal diamines in 80–97% yields with 93–95% enantioselectivities.

U2 - 10.1039/c5ob01243k

DO - 10.1039/c5ob01243k

M3 - Journal article

SN - 1477-0520

VL - 13

SP - 8425

EP - 8428

JO - Organic and Biomolecular Chemistry

JF - Organic and Biomolecular Chemistry

IS - 31

ER -

Iridium/copper-cocatalyzed asymmetric ring opening reaction of azabenzonorbornadienes with amines

Abstract

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