Iridium/copper-cocatalyzed asymmetric ring opening reaction of azabenzonorbornadienes with amines

Chaoyuan Zeng, Fan Yang, Jingchao Chen, Jun Wang*, Baomin Fan

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

A combination of iridium/copper associated with (R)-Difluorphos catalyst for the asymmetric ring opening reaction of azabenzonorbornadienes with amines was developed, which afforded chiral trans-vicinal diamines in 80–97% yields with 93–95% enantioselectivities.

Original languageEnglish
Pages (from-to)8425-8428
JournalOrganic and Biomolecular Chemistry
Volume13
Issue number31
DOIs
Publication statusPublished - 2015

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