@article{0ef55809925f4e948618102ee8a20763,
title = "Iridium-based probe for luminescent nitric oxide monitoring in live cells",
abstract = "Nitric oxide (NO) is an intra- and extracellular messenger with important functions during human physiology process. A long-lived luminescent iridium(III) complex probe 1 has been designed and synthesized for the monitoring of NO controllably released from sodium nitroprusside (SNP). Probe 1 displayed a 15-fold switch-on luminescence in the presence of SNP at 580 nm. The probe exhibited a linear response towards SNP between 5 to 25 μM with detection limit at 0.18 μM. Importantly, the luminescent switch-on detection of NO in HeLa cells was demonstrated. Overall, complex 1 has the potential to be applied for NO tracing in complicated cellular environment.",
author = "Chun Wu and Wu, {Ke Jia} and Kang, {Tian Shu} and Wang, {Hui Min David} and Leung, {Chung Hang} and Liu, {Jin Biao} and Ma, {Dik Lung}",
note = "Funding Information: This work is supported by Hong Kong Baptist University (FRG2/16-17/007, FRG2/17-18/003), the Health and Medical Research Fund (HMRF/14150561), the Research Grants Council (HKBU/12301115), the National Natural Science Foundation of China (21575121, 21775131, 21628502), the Hong Kong Baptist University Century Club Sponsorship Scheme 2018, the Interdisciplinary Research Matching Scheme (RC-IRMS/15-16/03), Innovation and Technology Fund (ITS/260/16FX), Collaborative Research Fund (C5026-16G), Matching Proof of Concept Fund (MPCF-001-2017/18), the Science and Technology Development Fund, Macao SAR (077/2016/ A2), the University of Macau (MYRG2016-00151-ICMS-QRCM), and the Natural Science Foundation of Jiangxi Province (20171BAB213008).",
year = "2018",
month = dec,
day = "1",
doi = "10.1038/s41598-018-30991-9",
language = "English",
volume = "8",
journal = "Scientific Reports",
issn = "2045-2322",
publisher = "Nature Publishing Group",
number = "1",
}