TY - JOUR
T1 - OXTR rs53576 polymorphism impacts interpersonal adaptability
T2 - Dispositional forgiveness as a mediator
AU - Zhao, Jing
AU - Yang, Yafang
AU - Li, Xiaohan
AU - Zheng, Linfeng
AU - Xue, Mengying
AU - Zhang, Mengfei
AU - Wang, Chunlan
AU - Yu, Rongjun
AU - Gong, Pingyuan
N1 - Funding Information:
The Natural Science Foundation of China (31640037) provided support to Pingyuan Gong to conduct this research.
Publisher Copyright:
© 2018 Elsevier Ltd.
PY - 2019/5
Y1 - 2019/5
N2 - Polymorphisms in the oxytocin receptor (OXTR) gene have been shown to be related to individual differences in social skills that are important for building and maintaining social relationships, such as the capability to efficiently process social information and regulate emotions. However, what remains unclear is the potential roles of OXTR polymorphisms in interpersonal adaptability, namely the ability to cope with the situational demands of interpersonal interactions. In this study, we examined the roles of OXTR rs53576 polymorphism in interpersonal adaptability, empathic perception, and dispositional forgiveness in a cohort of 573 college freshmen. The results indicated that the scores on interpersonal adaptability and dispositional forgiveness, apart from empathic perception, increased as functions of the number of G alleles of OXTR rs53576. Moreover, dispositional forgiveness, but not empathic perception, mediated the association between OXTR rs53576 and interpersonal adaptability. The findings highlight the influences of the OXTR gene on adaptive interpersonal interactions, especially when individuals face changing social situations.
AB - Polymorphisms in the oxytocin receptor (OXTR) gene have been shown to be related to individual differences in social skills that are important for building and maintaining social relationships, such as the capability to efficiently process social information and regulate emotions. However, what remains unclear is the potential roles of OXTR polymorphisms in interpersonal adaptability, namely the ability to cope with the situational demands of interpersonal interactions. In this study, we examined the roles of OXTR rs53576 polymorphism in interpersonal adaptability, empathic perception, and dispositional forgiveness in a cohort of 573 college freshmen. The results indicated that the scores on interpersonal adaptability and dispositional forgiveness, apart from empathic perception, increased as functions of the number of G alleles of OXTR rs53576. Moreover, dispositional forgiveness, but not empathic perception, mediated the association between OXTR rs53576 and interpersonal adaptability. The findings highlight the influences of the OXTR gene on adaptive interpersonal interactions, especially when individuals face changing social situations.
KW - Empathic perception
KW - Forgiveness
KW - Interpersonal adaptability
KW - Oxytocin receptor gene
KW - Polymorphism
UR - http://www.scopus.com/inward/record.url?scp=85059243288&partnerID=8YFLogxK
U2 - 10.1016/j.psyneuen.2018.12.240
DO - 10.1016/j.psyneuen.2018.12.240
M3 - Journal article
C2 - 30605805
AN - SCOPUS:85059243288
SN - 0306-4530
VL - 103
SP - 8
EP - 13
JO - Psychoneuroendocrinology
JF - Psychoneuroendocrinology
ER -