Investigation of N-methyl-D-aspartate induced mechanical behavior of neuroblastoma cells using atomic force microscopy

Yuqiang Fang; King W.C. Lai; Catherine Y.Y. Iu; Cathy N.P. Lui; Carmen K.M. Fung; Hung Wing LI; Kin Lam YUNG; Ning Xi

doi:10.1109/NANO.2013.6720884

Investigation of N-methyl-D-aspartate induced mechanical behavior of neuroblastoma cells using atomic force microscopy

Yuqiang Fang
, King W.C. Lai
, Catherine Y.Y. Iu
, Cathy N.P. Lui
, Carmen K.M. Fung
, Hung Wing LI
, Kin Lam YUNG
, Ning Xi

Research output: Chapter in book/report/conference proceeding › Conference proceeding › peer-review

Abstract

Physiological conditions of biological samples are regulated by many different parameters including mechanical and biochemical factors etc. Single-cell studies of these parameters are challenging by using conventional bioanalysis methods. However, with the recent advancement in nanotechnology, single-molecule and single-cell analysis is much more accessible. Understanding the changes of neuroblastoma cells in different mechanisms is critical for fundamental research in neurosciences. Here, we investigate the mechanical behavior of SH-SY5Y cells using atomic force microscopy. Topographic imaging of the cells and real-time quantitative analysis of their mechanical properties will be presented in the paper.

Original language	English
Title of host publication	2013 13th IEEE International Conference on Nanotechnology, IEEE-NANO 2013
Publisher	IEEE
Pages	329-332
Number of pages	4
ISBN (Electronic)	9781479906765, 9781479906758
DOIs	https://doi.org/10.1109/NANO.2013.6720884
Publication status	Published - 5 Aug 2013
Event	2013 13th IEEE International Conference on Nanotechnology, IEEE-NANO 2013 - Beijing, China Duration: 5 Aug 2013 → 8 Aug 2013

Publication series

Name	Proceedings of the IEEE Conference on Nanotechnology
ISSN (Print)	1944-9399
ISSN (Electronic)	1944-9380

Conference

Conference	2013 13th IEEE International Conference on Nanotechnology, IEEE-NANO 2013
Country/Territory	China
City	Beijing
Period	5/08/13 → 8/08/13

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This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1109/NANO.2013.6720884

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Fang, Y., Lai, K. W. C., Iu, C. Y. Y., Lui, C. N. P., Fung, C. K. M., LI, H. W., YUNG, K. L., & Xi, N. (2013). Investigation of N-methyl-D-aspartate induced mechanical behavior of neuroblastoma cells using atomic force microscopy. In 2013 13th IEEE International Conference on Nanotechnology, IEEE-NANO 2013 (pp. 329-332). (Proceedings of the IEEE Conference on Nanotechnology). IEEE. https://doi.org/10.1109/NANO.2013.6720884

@inproceedings{87da49f4602e441e8936b332d124a7e8,

title = "Investigation of N-methyl-D-aspartate induced mechanical behavior of neuroblastoma cells using atomic force microscopy",

abstract = "Physiological conditions of biological samples are regulated by many different parameters including mechanical and biochemical factors etc. Single-cell studies of these parameters are challenging by using conventional bioanalysis methods. However, with the recent advancement in nanotechnology, single-molecule and single-cell analysis is much more accessible. Understanding the changes of neuroblastoma cells in different mechanisms is critical for fundamental research in neurosciences. Here, we investigate the mechanical behavior of SH-SY5Y cells using atomic force microscopy. Topographic imaging of the cells and real-time quantitative analysis of their mechanical properties will be presented in the paper.",

author = "Yuqiang Fang and Lai, \{King W.C.\} and Iu, \{Catherine Y.Y.\} and Lui, \{Cathy N.P.\} and Fung, \{Carmen K.M.\} and LI, \{Hung Wing\} and YUNG, \{Kin Lam\} and Ning Xi",

year = "2013",

month = aug,

day = "5",

doi = "10.1109/NANO.2013.6720884",

language = "English",

series = "Proceedings of the IEEE Conference on Nanotechnology",

publisher = "IEEE",

pages = "329--332",

booktitle = "2013 13th IEEE International Conference on Nanotechnology, IEEE-NANO 2013",

address = "United States",

}

Fang, Y, Lai, KWC, Iu, CYY, Lui, CNP, Fung, CKM, LI, HW, YUNG, KL & Xi, N 2013, Investigation of N-methyl-D-aspartate induced mechanical behavior of neuroblastoma cells using atomic force microscopy. in 2013 13th IEEE International Conference on Nanotechnology, IEEE-NANO 2013. Proceedings of the IEEE Conference on Nanotechnology, IEEE, pp. 329-332, 2013 13th IEEE International Conference on Nanotechnology, IEEE-NANO 2013, Beijing, China, 5/08/13. https://doi.org/10.1109/NANO.2013.6720884

Investigation of N-methyl-D-aspartate induced mechanical behavior of neuroblastoma cells using atomic force microscopy. / Fang, Yuqiang; Lai, King W.C.; Iu, Catherine Y.Y. et al.
2013 13th IEEE International Conference on Nanotechnology, IEEE-NANO 2013. IEEE, 2013. p. 329-332 (Proceedings of the IEEE Conference on Nanotechnology).

Research output: Chapter in book/report/conference proceeding › Conference proceeding › peer-review

TY - GEN

T1 - Investigation of N-methyl-D-aspartate induced mechanical behavior of neuroblastoma cells using atomic force microscopy

AU - Fang, Yuqiang

AU - Lai, King W.C.

AU - Iu, Catherine Y.Y.

AU - Lui, Cathy N.P.

AU - Fung, Carmen K.M.

AU - LI, Hung Wing

AU - YUNG, Kin Lam

AU - Xi, Ning

PY - 2013/8/5

Y1 - 2013/8/5

N2 - Physiological conditions of biological samples are regulated by many different parameters including mechanical and biochemical factors etc. Single-cell studies of these parameters are challenging by using conventional bioanalysis methods. However, with the recent advancement in nanotechnology, single-molecule and single-cell analysis is much more accessible. Understanding the changes of neuroblastoma cells in different mechanisms is critical for fundamental research in neurosciences. Here, we investigate the mechanical behavior of SH-SY5Y cells using atomic force microscopy. Topographic imaging of the cells and real-time quantitative analysis of their mechanical properties will be presented in the paper.

AB - Physiological conditions of biological samples are regulated by many different parameters including mechanical and biochemical factors etc. Single-cell studies of these parameters are challenging by using conventional bioanalysis methods. However, with the recent advancement in nanotechnology, single-molecule and single-cell analysis is much more accessible. Understanding the changes of neuroblastoma cells in different mechanisms is critical for fundamental research in neurosciences. Here, we investigate the mechanical behavior of SH-SY5Y cells using atomic force microscopy. Topographic imaging of the cells and real-time quantitative analysis of their mechanical properties will be presented in the paper.

UR - https://www.scopus.com/pages/publications/84894160019

U2 - 10.1109/NANO.2013.6720884

DO - 10.1109/NANO.2013.6720884

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T3 - Proceedings of the IEEE Conference on Nanotechnology

SP - 329

EP - 332

BT - 2013 13th IEEE International Conference on Nanotechnology, IEEE-NANO 2013

PB - IEEE

T2 - 2013 13th IEEE International Conference on Nanotechnology, IEEE-NANO 2013

Y2 - 5 August 2013 through 8 August 2013

ER -

Investigation of N-methyl-D-aspartate induced mechanical behavior of neuroblastoma cells using atomic force microscopy

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