Influence of Magnolol on the bystander effect induced by alpha-particle irradiation

T. P.W. Wong, Y. L. Law, Anfernee K W TSE, W. F. Fong, K. N. Yu*

*Corresponding author for this work

Research output: Contribution to journalJournal articlepeer-review

5 Citations (Scopus)

Abstract

In this work, the influence of Magnolol on the bystander effect in alpha-particle irradiated Chinese hamster ovary (CHO) cells was examined. The bystander effect was studied through medium transfer experiments. Cytokinesis-block micronucleus (CBMN) assay was performed to quantify the chromosome damage induced by alpha-particle irradiation. Our results showed that the alpha-particle induced micronuclei (MN) frequencies were suppressed with the presence of Magnolol.

Original languageEnglish
Pages (from-to)718-721
Number of pages4
JournalApplied Radiation and Isotopes
Volume68
Issue number4-5
DOIs
Publication statusPublished - Apr 2010

Scopus Subject Areas

  • Radiation

User-Defined Keywords

  • Alpha-particle
  • Bystander effect
  • CHO cells
  • Magnolol

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