Influence of Magnolol on the bystander effect induced by alpha-particle irradiation

T. P.W. Wong; Y. L. Law; A. K.W. Tse; W. F. Fong; K. N. Yu

doi:10.1016/j.apradiso.2009.09.034

Influence of Magnolol on the bystander effect induced by alpha-particle irradiation

T. P.W. Wong, Y. L. Law, A. K.W. Tse, W. F. Fong, K. N. Yu^*

^*Corresponding author for this work

Chinese Medicine - Teaching and Research Division

Research output: Contribution to journal › Journal article › peer-review

5 Citations (Scopus)

Abstract

In this work, the influence of Magnolol on the bystander effect in alpha-particle irradiated Chinese hamster ovary (CHO) cells was examined. The bystander effect was studied through medium transfer experiments. Cytokinesis-block micronucleus (CBMN) assay was performed to quantify the chromosome damage induced by alpha-particle irradiation. Our results showed that the alpha-particle induced micronuclei (MN) frequencies were suppressed with the presence of Magnolol.

Original language	English
Pages (from-to)	718-721
Number of pages	4
Journal	Applied Radiation and Isotopes
Volume	68
Issue number	4-5
DOIs	https://doi.org/10.1016/j.apradiso.2009.09.034
Publication status	Published - Apr 2010

Scopus Subject Areas

Radiation

User-Defined Keywords

Alpha-particle
Bystander effect
CHO cells
Magnolol

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10.1016/j.apradiso.2009.09.034

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@article{d9230cdc9cb448d2bae7b7c47e975f56,

title = "Influence of Magnolol on the bystander effect induced by alpha-particle irradiation",

abstract = "In this work, the influence of Magnolol on the bystander effect in alpha-particle irradiated Chinese hamster ovary (CHO) cells was examined. The bystander effect was studied through medium transfer experiments. Cytokinesis-block micronucleus (CBMN) assay was performed to quantify the chromosome damage induced by alpha-particle irradiation. Our results showed that the alpha-particle induced micronuclei (MN) frequencies were suppressed with the presence of Magnolol.",

keywords = "Alpha-particle, Bystander effect, CHO cells, Magnolol",

author = "Wong, {T. P.W.} and Law, {Y. L.} and Tse, {A. K.W.} and Fong, {W. F.} and Yu, {K. N.}",

year = "2010",

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doi = "10.1016/j.apradiso.2009.09.034",

language = "English",

volume = "68",

pages = "718--721",

journal = "Applied Radiation and Isotopes",

issn = "0969-8043",

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TY - JOUR

T1 - Influence of Magnolol on the bystander effect induced by alpha-particle irradiation

AU - Wong, T. P.W.

AU - Law, Y. L.

AU - Tse, A. K.W.

AU - Fong, W. F.

AU - Yu, K. N.

PY - 2010/4

Y1 - 2010/4

N2 - In this work, the influence of Magnolol on the bystander effect in alpha-particle irradiated Chinese hamster ovary (CHO) cells was examined. The bystander effect was studied through medium transfer experiments. Cytokinesis-block micronucleus (CBMN) assay was performed to quantify the chromosome damage induced by alpha-particle irradiation. Our results showed that the alpha-particle induced micronuclei (MN) frequencies were suppressed with the presence of Magnolol.

AB - In this work, the influence of Magnolol on the bystander effect in alpha-particle irradiated Chinese hamster ovary (CHO) cells was examined. The bystander effect was studied through medium transfer experiments. Cytokinesis-block micronucleus (CBMN) assay was performed to quantify the chromosome damage induced by alpha-particle irradiation. Our results showed that the alpha-particle induced micronuclei (MN) frequencies were suppressed with the presence of Magnolol.

KW - Alpha-particle

KW - Bystander effect

KW - CHO cells

KW - Magnolol

UR - http://www.scopus.com/inward/record.url?scp=77649233302&partnerID=8YFLogxK

U2 - 10.1016/j.apradiso.2009.09.034

DO - 10.1016/j.apradiso.2009.09.034

M3 - Journal article

C2 - 19857974

AN - SCOPUS:77649233302

SN - 0969-8043

VL - 68

SP - 718

EP - 721

JO - Applied Radiation and Isotopes

JF - Applied Radiation and Isotopes

IS - 4-5

ER -

Influence of Magnolol on the bystander effect induced by alpha-particle irradiation

Abstract

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