Inflammatory properties of ribosome-inactivating protein momorcharin derived from bitter melon: abridged secondary publication

Yingjie Chen; Zhiling Yu; Anfernee K W Tse

Inflammatory properties of ribosome-inactivating protein momorcharin derived from bitter melon: abridged secondary publication

Yingjie Chen, Zhiling Yu, Anfernee K W Tse^*

^*Corresponding author for this work

Research output: Contribution to journal › Journal article › peer-review

Abstract

Key Messages
1. The inflammatory responses induced by alpha-momorcharin (α-MMC) derived from Momordica charantia (bitter melon) were studied.
2. α-MMC induced cytokines release in human monocytic THP-1 cells.
3. α-MMC-induced inflammatory gene expression were mediated by activation of IKK-NF-κB and JNK pathways.
4. α-MMC induced inflammatory responses in vivo.

Original language	English
Pages (from-to)	14-17
Number of pages	4
Journal	Hong Kong Medical Journal
Volume	27
Issue number	3 (Suppl 2)
Publication status	Published - Jun 2021

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@article{dca7aa4b42f5448986c223e872cf0ea4,

title = "Inflammatory properties of ribosome-inactivating protein momorcharin derived from bitter melon: abridged secondary publication",

abstract = "Key Messages1. The inflammatory responses induced by alpha-momorcharin (α-MMC) derived from Momordica charantia (bitter melon) were studied.2. α-MMC induced cytokines release in human monocytic THP-1 cells.3. α-MMC-induced inflammatory gene expression were mediated by activation of IKK-NF-κB and JNK pathways.4. α-MMC induced inflammatory responses in vivo.",

author = "Yingjie Chen and Zhiling Yu and Tse, {Anfernee K W}",

note = "Funding information: This study was supported by the Health and Medical Research Fund, Food and Health Bureau, Hong Kong SAR Government (#11122441). The full report is available from the Health and Medical Research Fund website (https://rfs1.fhb.gov.hk/index.html). Publisher copyright: {\textcopyright} 2021 Administering Institution and Hong Kong SAR Government",

year = "2021",

month = jun,

language = "English",

volume = "27",

pages = "14--17",

journal = "Hong Kong Medical Journal",

issn = "1024-2708",

publisher = "Hong Kong Academy of Medicine Press",

number = "3 (Suppl 2)",

}

TY - JOUR

T1 - Inflammatory properties of ribosome-inactivating protein momorcharin derived from bitter melon

T2 - abridged secondary publication

AU - Chen, Yingjie

AU - Yu, Zhiling

AU - Tse, Anfernee K W

N1 - Funding information: This study was supported by the Health and Medical Research Fund, Food and Health Bureau, Hong Kong SAR Government (#11122441). The full report is available from the Health and Medical Research Fund website (https://rfs1.fhb.gov.hk/index.html). Publisher copyright: © 2021 Administering Institution and Hong Kong SAR Government

PY - 2021/6

Y1 - 2021/6

N2 - Key Messages1. The inflammatory responses induced by alpha-momorcharin (α-MMC) derived from Momordica charantia (bitter melon) were studied.2. α-MMC induced cytokines release in human monocytic THP-1 cells.3. α-MMC-induced inflammatory gene expression were mediated by activation of IKK-NF-κB and JNK pathways.4. α-MMC induced inflammatory responses in vivo.

AB - Key Messages1. The inflammatory responses induced by alpha-momorcharin (α-MMC) derived from Momordica charantia (bitter melon) were studied.2. α-MMC induced cytokines release in human monocytic THP-1 cells.3. α-MMC-induced inflammatory gene expression were mediated by activation of IKK-NF-κB and JNK pathways.4. α-MMC induced inflammatory responses in vivo.

UR - https://www.hkmj.org/abstracts/v27n3%20Suppl%202/toc.htm

M3 - Journal article

SN - 1024-2708

VL - 27

SP - 14

EP - 17

JO - Hong Kong Medical Journal

JF - Hong Kong Medical Journal

IS - 3 (Suppl 2)

ER -

Inflammatory properties of ribosome-inactivating protein momorcharin derived from bitter melon: abridged secondary publication

Abstract

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