IGESS: A statistical approach to integrating individual-level genotype data and summary statistics in genome-wide association studies

Keyphrases

• Genome-wide Association Study 100%
• Genotype Data 100%
• Statistical Power 100%
• Risk Prediction 66%
• Risk Variant 66%
• Publicly Available 33%
• Prediction Accuracy 33%
• Simulation Study 33%
• Integrative Analysis 33%
• Accuracy Improvement 33%
• Genome-wide Analysis 33%
• Crohn's Disease 33%
• Complex Phenotypes 33%
• WTCCC 33%
• Variational Inference 33%
• Comprehensive Simulation 33%
• Limited Samples 33%
• Statistic Data 33%
• Polygenicity 33%
• Individual-level Data 33%
• Multiple Variants 33%

Biochemistry, Genetics and Molecular Biology

• Genotyping 100%
• Genome-Wide Association Study 100%
• Sample Size 66%
• Genome Wide Association Study 33%

Mathematics

• Statistical Approach 100%
• Summary Statistic 100%
• Statistical Power 50%
• Simulation Study 16%
• Open Question 16%