Hypertension and Associated Risk Factors among Children with Intellectual Disability: A Cross-Sectional Study

Yan Sun, Rashmi Supriya, Yang Gemma Gao*, Dan Tao, Siyue Yu, Aiwei Wang, Hardaway Chun-Kwan Chan, Xiaoting Ou, Jingjing Wang, Julien Baker

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)

Abstract

To investigate the prevalence of hypertension and associated risk factors in Chinese children with intellectual disability, a cross-sectional study was conducted in a sample of 558 children with intellectual disability aged 6–18 years in Hong Kong, and 452 (81.0%) with valid data were included in the data analysis. Blood pressure was measured according to a standard protocol. Hypertension was defined using the age-, gender-, and height-specific classification criteria recommended by the 2018 Chinese Guidelines for Children. Multivariate and hierarchical logistic regression was fitted to examine the associations of hypertension with potential risk factors. Overall, 31.4% of the participants were classified as having hypertension. Obese children were more likely to develop hypertension than non-obese children (adjusted OR = 2.77, 95% CI: 1.28, 5.99, p = 0.010). A paternal education of college or above and a paternal occupation of clerks, sales representatives, and workers were also associated with an increased risk of hypertension. The prevalence of hypertension is high among Chinese children with intellectual disability. Obesity was the strongest risk factor. Further longitudinal studies are warranted to confirm our findings. Nevertheless, preventions against obesity are promising to receive doubled benefits in reducing both obesity and hypertension, given its strong relationship with hypertension in this special population.
Original languageEnglish
Article number3127
Number of pages14
JournalNutrients
Volume14
Issue number15
Early online date29 Jul 2022
DOIs
Publication statusPublished - 1 Aug 2022

Scopus Subject Areas

  • Food Science
  • Nutrition and Dietetics

User-Defined Keywords

  • children
  • cross-sectional study
  • hypertension
  • intellectual disability
  • risk factor

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