TY - JOUR
T1 - Hypertension and Associated Risk Factors among Children with Intellectual Disability: A Cross-Sectional Study
AU - Sun, Yan
AU - Supriya, Rashmi
AU - Gao, Yang Gemma
AU - Tao, Dan
AU - Yu, Siyue
AU - Wang, Aiwei
AU - Chan, Hardaway Chun-Kwan
AU - Ou, Xiaoting
AU - Wang, Jingjing
AU - Baker, Julien
N1 - Funding Information:
This study has received funding support from the Health Care and Promotion Scheme under the Health and Medical Research Fund administered by the Food and Health Bureau of Hong Kong, Grant number: 01170068, and the Faculty Research Grant, Hong Kong Baptist University, Grant number: FRG1/13-14/067.
Publisher Copyright:
© 2022 by the authors.
PY - 2022/8/1
Y1 - 2022/8/1
N2 - To investigate the prevalence of hypertension and associated risk factors in Chinese children with intellectual disability, a cross-sectional study was conducted in a sample of 558 children with intellectual disability aged 6–18 years in Hong Kong, and 452 (81.0%) with valid data were included in the data analysis. Blood pressure was measured according to a standard protocol. Hypertension was defined using the age-, gender-, and height-specific classification criteria recommended by the 2018 Chinese Guidelines for Children. Multivariate and hierarchical logistic regression was fitted to examine the associations of hypertension with potential risk factors. Overall, 31.4% of the participants were classified as having hypertension. Obese children were more likely to develop hypertension than non-obese children (adjusted OR = 2.77, 95% CI: 1.28, 5.99, p = 0.010). A paternal education of college or above and a paternal occupation of clerks, sales representatives, and workers were also associated with an increased risk of hypertension. The prevalence of hypertension is high among Chinese children with intellectual disability. Obesity was the strongest risk factor. Further longitudinal studies are warranted to confirm our findings. Nevertheless, preventions against obesity are promising to receive doubled benefits in reducing both obesity and hypertension, given its strong relationship with hypertension in this special population.
AB - To investigate the prevalence of hypertension and associated risk factors in Chinese children with intellectual disability, a cross-sectional study was conducted in a sample of 558 children with intellectual disability aged 6–18 years in Hong Kong, and 452 (81.0%) with valid data were included in the data analysis. Blood pressure was measured according to a standard protocol. Hypertension was defined using the age-, gender-, and height-specific classification criteria recommended by the 2018 Chinese Guidelines for Children. Multivariate and hierarchical logistic regression was fitted to examine the associations of hypertension with potential risk factors. Overall, 31.4% of the participants were classified as having hypertension. Obese children were more likely to develop hypertension than non-obese children (adjusted OR = 2.77, 95% CI: 1.28, 5.99, p = 0.010). A paternal education of college or above and a paternal occupation of clerks, sales representatives, and workers were also associated with an increased risk of hypertension. The prevalence of hypertension is high among Chinese children with intellectual disability. Obesity was the strongest risk factor. Further longitudinal studies are warranted to confirm our findings. Nevertheless, preventions against obesity are promising to receive doubled benefits in reducing both obesity and hypertension, given its strong relationship with hypertension in this special population.
KW - children
KW - cross-sectional study
KW - hypertension
KW - intellectual disability
KW - risk factor
UR - http://www.scopus.com/inward/record.url?scp=85136342149&partnerID=8YFLogxK
U2 - 10.3390/nu14153127
DO - 10.3390/nu14153127
M3 - Journal article
SN - 2072-6643
VL - 14
JO - Nutrients
JF - Nutrients
IS - 15
M1 - 3127
ER -
