真实世界研究中如何关注中西药相互作用的安全性评价

Translated title of the contribution: How to focus on the safety assessment of herb-drug interaction in real world studies

胡智超, 葛利达, 柳涛, 钟丽丹*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

真实世界研究有助于最大限度地反映临床事实,其方法学特点符合中医辨证论治的临床特色及当前临床中西药联用的医疗现实,有助于更高效、经济地解决中西药相互作用安全性评估问题。而在设计研究时,须特别注意真实世界数据的“关联性”与“有效性”,规范研究的数据内容与采集流程。可通过主动呈报方式,基于医疗系统互通、全民保险资料库的大数据研究并与精准医疗研究相结合是未来中西药联用安全性评估的重要研究方向。

Real-world studies (RWSs) data are based on real medical scenes and reflect clinical facts. Besides, RWSs adapts to the characteristics of therapeutic principles of traditional Chinese medicine and the medical reality of the combination of Western and traditional Chinese medicine, which makes the safety assessment of herb-drug interaction more efficient and economical. During RWSs, more attention should be paid on the validity and reliability of data, especially the standardization of the data collection process and its contents. The safety assessment of herb-drug interaction will combine the methods of active surveillance study, big data analysis, and be based on precision medicine in the future.

Translated title of the contributionHow to focus on the safety assessment of herb-drug interaction in real world studies
Original languageChinese (Simplified)
Pages (from-to)1158-1162
Number of pages5
Journal中国循证医学杂志
Volume18
Issue number11
DOIs
Publication statusPublished - Nov 2018

Scopus Subject Areas

  • Medicine(all)

User-Defined Keywords

  • Active surveillance
  • Herb-drug interaction
  • Real-world studies
  • Safety assessment

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