Highly selective detection of Pd2+ ion in aqueous solutions with rhodamine-based colorimetric and fluorescent chemosensors

Fung Kit Tang; Sing Ming Chan; Tao Wang; Chak Shing Kwan; Regina Huang; Zongwei Cai; Ken C F Leung

doi:10.1016/j.talanta.2019.120634

Highly selective detection of Pd²⁺ ion in aqueous solutions with rhodamine-based colorimetric and fluorescent chemosensors

Fung Kit Tang, Sing Ming Chan, Tao Wang, Chak Shing Kwan, Regina Huang, Zongwei Cai^*, Ken C F Leung^*

^*Corresponding author for this work

Research output: Contribution to journal › Journal article › peer-review

26 Citations (Scopus)

Abstract

In this study, we report a new class of rhodamine-based fluorescent sensors for highly selective and sensitive detection of Pd²⁺ ions in aqueous medium. A rhodamine-based palladium sensor RPS and a coumarin-rhodamine Förster resonance energy transfer (FRET)-pair based palladium sensor FPS were synthesized with the designed podand ligand for Pd²⁺ ion recognition. They showed both colorimetric change and fluorometric change in the presence of Pd²⁺ ion due to the opening of their spirolactam rings. Both chemosensors are highly selective to Pd²⁺ over the other 24 different metal ions and they are selective to palladium species in +2 oxidation state, RPS showed a 70-fold fluorescent turn-on while FPS showed a 1.75-fold ratiometric change at I₅₉₉/I₄₇₀. Furthermore, RPS showed low cell cytotoxicity and it was successfully used to image Pd²⁺ in BEAS-2B lung epithelial cells.

Original language	English
Article number	120634
Journal	Talanta
Volume	210
DOIs	https://doi.org/10.1016/j.talanta.2019.120634
Publication status	Published - 1 Apr 2020

Scopus Subject Areas

Analytical Chemistry

User-Defined Keywords

Chemosensor
Fluorescence
Palladium
Rhodamine

Access to Document

10.1016/j.talanta.2019.120634

Cite this

@article{a7f8ca16212e497a9f06d3201ed255ab,

title = "Highly selective detection of Pd2+ ion in aqueous solutions with rhodamine-based colorimetric and fluorescent chemosensors",

abstract = "In this study, we report a new class of rhodamine-based fluorescent sensors for highly selective and sensitive detection of Pd2+ ions in aqueous medium. A rhodamine-based palladium sensor RPS and a coumarin-rhodamine F{\"o}rster resonance energy transfer (FRET)-pair based palladium sensor FPS were synthesized with the designed podand ligand for Pd2+ ion recognition. They showed both colorimetric change and fluorometric change in the presence of Pd2+ ion due to the opening of their spirolactam rings. Both chemosensors are highly selective to Pd2+ over the other 24 different metal ions and they are selective to palladium species in +2 oxidation state, RPS showed a 70-fold fluorescent turn-on while FPS showed a 1.75-fold ratiometric change at I599/I470. Furthermore, RPS showed low cell cytotoxicity and it was successfully used to image Pd2+ in BEAS-2B lung epithelial cells.",

keywords = "Chemosensor, Fluorescence, Palladium, Rhodamine",

author = "Tang, {Fung Kit} and Chan, {Sing Ming} and Tao Wang and Kwan, {Chak Shing} and Regina Huang and Zongwei Cai and Leung, {Ken C F}",

note = "Funding Information: This work was financially supported by the State Key Laboratory of Environmental and Biological Analysis (SKLP-1718-P03) from the Hong Kong Baptist University . We also thank Mr. W.S. Chung and Dr. L.S. Chan for the assistance of confocal laser scanning microscope. Appendix A ",

year = "2020",

month = apr,

day = "1",

doi = "10.1016/j.talanta.2019.120634",

language = "English",

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journal = "Talanta",

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T1 - Highly selective detection of Pd2+ ion in aqueous solutions with rhodamine-based colorimetric and fluorescent chemosensors

AU - Tang, Fung Kit

AU - Chan, Sing Ming

AU - Wang, Tao

AU - Kwan, Chak Shing

AU - Huang, Regina

AU - Cai, Zongwei

AU - Leung, Ken C F

N1 - Funding Information: This work was financially supported by the State Key Laboratory of Environmental and Biological Analysis (SKLP-1718-P03) from the Hong Kong Baptist University . We also thank Mr. W.S. Chung and Dr. L.S. Chan for the assistance of confocal laser scanning microscope. Appendix A

PY - 2020/4/1

Y1 - 2020/4/1

N2 - In this study, we report a new class of rhodamine-based fluorescent sensors for highly selective and sensitive detection of Pd2+ ions in aqueous medium. A rhodamine-based palladium sensor RPS and a coumarin-rhodamine Förster resonance energy transfer (FRET)-pair based palladium sensor FPS were synthesized with the designed podand ligand for Pd2+ ion recognition. They showed both colorimetric change and fluorometric change in the presence of Pd2+ ion due to the opening of their spirolactam rings. Both chemosensors are highly selective to Pd2+ over the other 24 different metal ions and they are selective to palladium species in +2 oxidation state, RPS showed a 70-fold fluorescent turn-on while FPS showed a 1.75-fold ratiometric change at I599/I470. Furthermore, RPS showed low cell cytotoxicity and it was successfully used to image Pd2+ in BEAS-2B lung epithelial cells.

AB - In this study, we report a new class of rhodamine-based fluorescent sensors for highly selective and sensitive detection of Pd2+ ions in aqueous medium. A rhodamine-based palladium sensor RPS and a coumarin-rhodamine Förster resonance energy transfer (FRET)-pair based palladium sensor FPS were synthesized with the designed podand ligand for Pd2+ ion recognition. They showed both colorimetric change and fluorometric change in the presence of Pd2+ ion due to the opening of their spirolactam rings. Both chemosensors are highly selective to Pd2+ over the other 24 different metal ions and they are selective to palladium species in +2 oxidation state, RPS showed a 70-fold fluorescent turn-on while FPS showed a 1.75-fold ratiometric change at I599/I470. Furthermore, RPS showed low cell cytotoxicity and it was successfully used to image Pd2+ in BEAS-2B lung epithelial cells.

KW - Chemosensor

KW - Fluorescence

KW - Palladium

KW - Rhodamine

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