Highly efficient Pd/tetraphosphine catalytic system for copper-free sonogashira reactions of aryl bromides with terminal alkynes

Keyphrases

• Catalytic System 100%
• High Efficiency 100%
• Tetraphosphine 100%
• Aryl Bromides 100%
• Terminal Alkynes 100%
• Copper-free Sonogashira Reaction 100%
• Low Catalyst Loading 50%
• Phenyl 50%
• In Situ 50%
• 31P NMR 50%
• TETRA 50%
• Active Catalyst 50%
• Cl 2 50%
• 1,2-Ethylenediamine 50%
• Bromide 50%
• Heteroaryl Bromides 50%
• Functional Group Tolerance 50%
• PDCs 50%
• Polydentate Ligands 50%
• Water Influence 50%

Chemistry

• Alkyne 100%
• Sonogashira Cross-Coupling 100%
• Phosphorus-31 Magnetic Resonance Spectroscopy 50%
• Ethylenediamine 50%