High-intensity interval exercise lowers postprandial glucose concentrations more in obese adults than lean adults

Zhaowei Kong, Qingde Shi*, Shengyan Sun, Tom K K Tong, Haifeng Zhang, Jinlei Nie

*Corresponding author for this work

Research output: Contribution to journalJournal articlepeer-review

7 Citations (Scopus)


Aims: To compare postprandial glucose responses to high-intensity interval exercise (HIE) between obese and lean individuals. Methods: Thirty healthy young adult males (15 obese, 15 lean) ate a standardised meal, then performed HIE (4 × 30-s Wingate cycling/4-min rest) or a no-exercise control trial (CON). Blood glucose was measured preprandially and up to 150 min postprandially. Results: Compared to CON, HIE reduced postprandial glucose concentrations at 120–150 min in obese (p < 0.001) and lean men (p < 0.05), with greater reductions in obese than lean subjects at 120 (−27.0% vs. −8.3%), 135 (−31.9% vs. −15.7%), and 150 min (−21.8% vs. −10.6%). The total glucose area under the curve (AUC) for the testing period was lower with HIE than CON among obese men (p < 0.05), but not lean men (p > 0.05). We found moderate correlations between body mass and postprandial glucose changes (r = 0.39–0.44, p < 0.05), and between glucose AUC and body mass and fat free mass (r = 0.39–0.48, p < 0.05). Conclusions: Our findings suggest that HIE may act as a time-efficient lifestyle intervention strategy for improving obesity-related diabetes risk factors, and might play a role in primary diabetes prevention for the healthy but sedentary population.

Original languageEnglish
Pages (from-to)568-573
Number of pages6
JournalPrimary Care Diabetes
Issue number6
Publication statusPublished - Dec 2019

Scopus Subject Areas

  • Internal Medicine
  • Endocrinology, Diabetes and Metabolism
  • Nutrition and Dietetics

User-Defined Keywords

  • Fat-free mass
  • Glycaemic control
  • Obesity
  • Sprint exercise
  • Wingate test


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