Hemiterpene glucosides with anti-platelet aggregation activities from Ilex pubescens

Zhi Hong Jiang; Jing Rong Wang; Min Li; Zhong Qiu Liu; Ka Yee Chau; Chi Zhao; Liang Liu

doi:10.1021/np049735y

Hemiterpene glucosides with anti-platelet aggregation activities from Ilex pubescens

Zhi Hong Jiang
, Jing Rong Wang
, Min Li
, Zhong Qiu Liu
, Ka Yee Chau
, Chi Zhao
, Liang Liu^*

^*Corresponding author for this work

Research output: Contribution to journal › Journal article › peer-review

51 Citations (Scopus)

Abstract

Two new hemiterpene glucosides named pubescenosides A and B were isolated from the root of Ilex pubescens. Their structures were elucidated on the basis of spectroscopic and chemical evidence as 2-(trans-caffeoyloxy)methyl-3-hydroxy- 1-butene-4-O-β-D-glucopyranoside and 2-hydroxymethyl-3-caffeoyloxy-1- butene-4-O-β-D-glucopyranoside, respectively. Pharmacological investigation on pubescenosides A and B indicated that both possess potent anti-platelet aggregation activities.

Original language	English
Pages (from-to)	397-399
Number of pages	3
Journal	Journal of Natural Products
Volume	68
Issue number	3
DOIs	https://doi.org/10.1021/np049735y
Publication status	Published - Mar 2005

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title = "Hemiterpene glucosides with anti-platelet aggregation activities from Ilex pubescens",

abstract = "Two new hemiterpene glucosides named pubescenosides A and B were isolated from the root of Ilex pubescens. Their structures were elucidated on the basis of spectroscopic and chemical evidence as 2-(trans-caffeoyloxy)methyl-3-hydroxy- 1-butene-4-O-β-D-glucopyranoside and 2-hydroxymethyl-3-caffeoyloxy-1- butene-4-O-β-D-glucopyranoside, respectively. Pharmacological investigation on pubescenosides A and B indicated that both possess potent anti-platelet aggregation activities.",

author = "Jiang, \{Zhi Hong\} and Wang, \{Jing Rong\} and Min Li and Liu, \{Zhong Qiu\} and Chau, \{Ka Yee\} and Chi Zhao and Liang Liu",

note = "This project was financially supported by Faculty Research Grants from Hong Kong Baptist University. ",

year = "2005",

month = mar,

doi = "10.1021/np049735y",

language = "English",

volume = "68",

pages = "397--399",

journal = "Journal of Natural Products",

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publisher = "American Chemical Society",

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TY - JOUR

T1 - Hemiterpene glucosides with anti-platelet aggregation activities from Ilex pubescens

AU - Jiang, Zhi Hong

AU - Wang, Jing Rong

AU - Li, Min

AU - Liu, Zhong Qiu

AU - Chau, Ka Yee

AU - Zhao, Chi

AU - Liu, Liang

N1 - This project was financially supported by Faculty Research Grants from Hong Kong Baptist University.

PY - 2005/3

Y1 - 2005/3

N2 - Two new hemiterpene glucosides named pubescenosides A and B were isolated from the root of Ilex pubescens. Their structures were elucidated on the basis of spectroscopic and chemical evidence as 2-(trans-caffeoyloxy)methyl-3-hydroxy- 1-butene-4-O-β-D-glucopyranoside and 2-hydroxymethyl-3-caffeoyloxy-1- butene-4-O-β-D-glucopyranoside, respectively. Pharmacological investigation on pubescenosides A and B indicated that both possess potent anti-platelet aggregation activities.

AB - Two new hemiterpene glucosides named pubescenosides A and B were isolated from the root of Ilex pubescens. Their structures were elucidated on the basis of spectroscopic and chemical evidence as 2-(trans-caffeoyloxy)methyl-3-hydroxy- 1-butene-4-O-β-D-glucopyranoside and 2-hydroxymethyl-3-caffeoyloxy-1- butene-4-O-β-D-glucopyranoside, respectively. Pharmacological investigation on pubescenosides A and B indicated that both possess potent anti-platelet aggregation activities.

UR - https://www.scopus.com/pages/publications/17444410341

U2 - 10.1021/np049735y

DO - 10.1021/np049735y

M3 - Journal article

C2 - 15787443

AN - SCOPUS:17444410341

SN - 0163-3864

VL - 68

SP - 397

EP - 399

JO - Journal of Natural Products

JF - Journal of Natural Products

IS - 3

ER -

Hemiterpene glucosides with anti-platelet aggregation activities from Ilex pubescens

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