Hemiterpene glucosides with anti-platelet aggregation activities from Ilex pubescens

Zhi Hong JIANG, Jing Rong Wang, Min LI, Zhong Qiu Liu, Ka Yee Chau, Chi Zhao, Liang LIU*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

41 Citations (Scopus)

Abstract

Two new hemiterpene glucosides named pubescenosides A and B were isolated from the root of Ilex pubescens. Their structures were elucidated on the basis of spectroscopic and chemical evidence as 2-(trans-caffeoyloxy)methyl-3-hydroxy- 1-butene-4-O-β-D-glucopyranoside and 2-hydroxymethyl-3-caffeoyloxy-1- butene-4-O-β-D-glucopyranoside, respectively. Pharmacological investigation on pubescenosides A and B indicated that both possess potent anti-platelet aggregation activities.

Original languageEnglish
Pages (from-to)397-399
Number of pages3
JournalJournal of Natural Products
Volume68
Issue number3
DOIs
Publication statusPublished - Mar 2005

Scopus Subject Areas

  • Analytical Chemistry
  • Molecular Medicine
  • Pharmacology
  • Pharmaceutical Science
  • Drug Discovery
  • Complementary and alternative medicine
  • Organic Chemistry

Fingerprint

Dive into the research topics of 'Hemiterpene glucosides with anti-platelet aggregation activities from Ilex pubescens'. Together they form a unique fingerprint.

Cite this