Hemiterpene glucosides with anti-platelet aggregation activities from Ilex pubescens

Zhi Hong Jiang, Jing Rong Wang, Min Li, Zhong Qiu Liu, Ka Yee Chau, Chi Zhao, Liang Liu*

*Corresponding author for this work

Research output: Contribution to journalJournal articlepeer-review

50 Citations (Scopus)


Two new hemiterpene glucosides named pubescenosides A and B were isolated from the root of Ilex pubescens. Their structures were elucidated on the basis of spectroscopic and chemical evidence as 2-(trans-caffeoyloxy)methyl-3-hydroxy- 1-butene-4-O-β-D-glucopyranoside and 2-hydroxymethyl-3-caffeoyloxy-1- butene-4-O-β-D-glucopyranoside, respectively. Pharmacological investigation on pubescenosides A and B indicated that both possess potent anti-platelet aggregation activities.

Original languageEnglish
Pages (from-to)397-399
Number of pages3
JournalJournal of Natural Products
Issue number3
Publication statusPublished - Mar 2005

Scopus Subject Areas

  • Analytical Chemistry
  • Molecular Medicine
  • Pharmacology
  • Pharmaceutical Science
  • Drug Discovery
  • Complementary and alternative medicine
  • Organic Chemistry


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