Gut microbiota and colorectal cancer metastasis

Zongmei Zheng, Xinxin Hou, Zhaoxiang Bian, Wei Jia*, Ling Zhao*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

9 Citations (Scopus)

Abstract

Gut microbiota play critical roles in the development of colorectal cancer (CRC) metastasis, but the underlying mechanisms remain elusive. This review discusses the molecular mechanisms by which the gut microbiota contribute to a tumor-permissive microenvironment and facilitate malignant transformation and dissemination of tumor cells, thereby mediating CRC metastasis.

Original languageEnglish
Article number216039
JournalCancer Letters
Volume555
Early online date15 Dec 2022
DOIs
Publication statusPublished - 28 Feb 2023

Scopus Subject Areas

  • Oncology
  • Cancer Research

User-Defined Keywords

  • Colorectal cancer
  • Gut microbiota
  • Metastasis
  • Tumor microenvironment

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