Group 8–9 Metal-Based Luminescent Chemosensors for Protein Biomarker Detection

Edmond Dik Lung MA*, Chun Wu, Guodong Li, Chung Hang Leung

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

4 Citations (Scopus)

Abstract

The development of transition metal complex-based luminescent chemosensors has recently aroused increasing interest for protein biomarker labelling and detection, especially for the real-time diagnosis and treatment of disease. This is owing to their unique photophysical properties, particularly their long-lived and environmentally sensitive emission, which can be easily controlled via the structural modification of ligands. In this overview, we highlight recent examples of protein biomarker detection using group 8–9 metal-based luminescent chemosensors, including the frequently employed ruthenium(II) and iridium(III) complexes. Various mechanisms and sensing modes are described and compared, and the outlook and future directions of this field are discussed as well.

Original languageEnglish
Pages (from-to)77-89
Number of pages13
JournalJournal of Analysis and Testing
Volume2
Issue number1
DOIs
Publication statusPublished - 1 Jan 2018

Scopus Subject Areas

  • Analytical Chemistry
  • Environmental Chemistry
  • Instrumentation
  • Spectroscopy
  • Electrochemistry
  • Materials Chemistry

User-Defined Keywords

  • Biomarker
  • Chemosensor
  • Luminescence
  • Metal complex

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