Green valorization of Chaenomelis Fructus agro-industrial by-products as a source of phenolics: Ultrasound-assisted extraction, adsorptive enrichment and quality control

Mengyang Hou; Yujuan Zhou; Chengyuan Lin; Jingchun Shi; Huidan Hou; Yanhua Ma; Lin Zhu; Zhaoxiang Bian

doi:10.1016/j.foodchem.2025.142908

Green valorization of Chaenomelis Fructus agro-industrial by-products as a source of phenolics: Ultrasound-assisted extraction, adsorptive enrichment and quality control

Mengyang Hou, Yujuan Zhou, Chengyuan Lin, Jingchun Shi, Huidan Hou, Yanhua Ma, Lin Zhu^*, Zhaoxiang Bian^*

^*Corresponding author for this work

Research output: Contribution to journal › Journal article › peer-review

Abstract

This study aimed to develop a green and efficient strategy for the recovery of bioactive phenolics from agro-industrial by-products (AIBPs) derived from Chaenomelis Fructus (CF). The peel of Chaenomelis Fructus (CFP) has a higher phenolic content compared to its leaves and seeds. The ultrasound-assisted extraction process for CFP total phenolics (CFPTP) was optimized using response surface methodology, achieving a yield of 216.27 ± 1.04 mg/g. ADS-17 resin exhibited higher adsorption-desorption capacity for CFPTP and was selected as the optimal resin. Studies on adsorption behavior confirmed adherence to pseudo-second order and Langmuir models, characterized by exothermicity, spontaneity, and entropy reduction. A chromatography enrichment process employing ADS-17 resin yielded a CFPTP-rich extract with a purity of 84.22 ± 1.57 %. Additionally, a UPLC-QqQ-MS/MS method was developed to simultaneously measure eight main phenolic compounds in CFPTP extracts. This study contributes to the transformation of CF AIBPs into valuable products rich in phenolics.

Original language	English
Article number	142908
Number of pages	10
Journal	Food Chemistry
Volume	472
DOIs	https://doi.org/10.1016/j.foodchem.2025.142908
Publication status	Published - 30 Apr 2025

Scopus Subject Areas

Analytical Chemistry
Food Science

User-Defined Keywords

Adsorptive enrichment
Chaenomelis Fructus
Phenolics
Ultrasound-assisted extraction
UPLC-QqQ-MS/MS

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.foodchem.2025.142908

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title = "Green valorization of Chaenomelis Fructus agro-industrial by-products as a source of phenolics: Ultrasound-assisted extraction, adsorptive enrichment and quality control",

abstract = "This study aimed to develop a green and efficient strategy for the recovery of bioactive phenolics from agro-industrial by-products (AIBPs) derived from Chaenomelis Fructus (CF). The peel of Chaenomelis Fructus (CFP) has a higher phenolic content compared to its leaves and seeds. The ultrasound-assisted extraction process for CFP total phenolics (CFPTP) was optimized using response surface methodology, achieving a yield of 216.27 ± 1.04 mg/g. ADS-17 resin exhibited higher adsorption-desorption capacity for CFPTP and was selected as the optimal resin. Studies on adsorption behavior confirmed adherence to pseudo-second order and Langmuir models, characterized by exothermicity, spontaneity, and entropy reduction. A chromatography enrichment process employing ADS-17 resin yielded a CFPTP-rich extract with a purity of 84.22 ± 1.57 %. Additionally, a UPLC-QqQ-MS/MS method was developed to simultaneously measure eight main phenolic compounds in CFPTP extracts. This study contributes to the transformation of CF AIBPs into valuable products rich in phenolics.",

keywords = "Adsorptive enrichment, Chaenomelis Fructus, Phenolics, Ultrasound-assisted extraction, UPLC-QqQ-MS/MS",

author = "Mengyang Hou and Yujuan Zhou and Chengyuan Lin and Jingchun Shi and Huidan Hou and Yanhua Ma and Lin Zhu and Zhaoxiang Bian",

note = "Funding Information: This work was supported by the Health@InnoHK Initiative Fund of the Hong Kong Special Administrative Region Government (ITC RC/IHK/4/7) and the Key-Area Research and Development Program of Guangdong Province (2020B1111110003). Publisher Copyright: {\textcopyright} 2025 Elsevier Ltd. All rights are reserved, including those for text and data mining, AI training, and similar technologies.",

year = "2025",

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doi = "10.1016/j.foodchem.2025.142908",

language = "English",

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T1 - Green valorization of Chaenomelis Fructus agro-industrial by-products as a source of phenolics

T2 - Ultrasound-assisted extraction, adsorptive enrichment and quality control

AU - Hou, Mengyang

AU - Zhou, Yujuan

AU - Lin, Chengyuan

AU - Shi, Jingchun

AU - Hou, Huidan

AU - Ma, Yanhua

AU - Zhu, Lin

AU - Bian, Zhaoxiang

N1 - Funding Information: This work was supported by the Health@InnoHK Initiative Fund of the Hong Kong Special Administrative Region Government (ITC RC/IHK/4/7) and the Key-Area Research and Development Program of Guangdong Province (2020B1111110003). Publisher Copyright: © 2025 Elsevier Ltd. All rights are reserved, including those for text and data mining, AI training, and similar technologies.

PY - 2025/4/30

Y1 - 2025/4/30

N2 - This study aimed to develop a green and efficient strategy for the recovery of bioactive phenolics from agro-industrial by-products (AIBPs) derived from Chaenomelis Fructus (CF). The peel of Chaenomelis Fructus (CFP) has a higher phenolic content compared to its leaves and seeds. The ultrasound-assisted extraction process for CFP total phenolics (CFPTP) was optimized using response surface methodology, achieving a yield of 216.27 ± 1.04 mg/g. ADS-17 resin exhibited higher adsorption-desorption capacity for CFPTP and was selected as the optimal resin. Studies on adsorption behavior confirmed adherence to pseudo-second order and Langmuir models, characterized by exothermicity, spontaneity, and entropy reduction. A chromatography enrichment process employing ADS-17 resin yielded a CFPTP-rich extract with a purity of 84.22 ± 1.57 %. Additionally, a UPLC-QqQ-MS/MS method was developed to simultaneously measure eight main phenolic compounds in CFPTP extracts. This study contributes to the transformation of CF AIBPs into valuable products rich in phenolics.

AB - This study aimed to develop a green and efficient strategy for the recovery of bioactive phenolics from agro-industrial by-products (AIBPs) derived from Chaenomelis Fructus (CF). The peel of Chaenomelis Fructus (CFP) has a higher phenolic content compared to its leaves and seeds. The ultrasound-assisted extraction process for CFP total phenolics (CFPTP) was optimized using response surface methodology, achieving a yield of 216.27 ± 1.04 mg/g. ADS-17 resin exhibited higher adsorption-desorption capacity for CFPTP and was selected as the optimal resin. Studies on adsorption behavior confirmed adherence to pseudo-second order and Langmuir models, characterized by exothermicity, spontaneity, and entropy reduction. A chromatography enrichment process employing ADS-17 resin yielded a CFPTP-rich extract with a purity of 84.22 ± 1.57 %. Additionally, a UPLC-QqQ-MS/MS method was developed to simultaneously measure eight main phenolic compounds in CFPTP extracts. This study contributes to the transformation of CF AIBPs into valuable products rich in phenolics.

KW - Adsorptive enrichment

KW - Chaenomelis Fructus

KW - Phenolics

KW - Ultrasound-assisted extraction

KW - UPLC-QqQ-MS/MS

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DO - 10.1016/j.foodchem.2025.142908

M3 - Journal article

AN - SCOPUS:85215416192

SN - 0308-8146

VL - 472

JO - Food Chemistry

JF - Food Chemistry

M1 - 142908

ER -

Green valorization of Chaenomelis Fructus agro-industrial by-products as a source of phenolics: Ultrasound-assisted extraction, adsorptive enrichment and quality control

Abstract

Scopus Subject Areas

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UN SDGs

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