Genetically encoded voltage indicators

Irene Mollinedo-Gajate; Chenchen Song; Thomas Knöpfel

doi:10.1007/978-981-15-8763-4_12

Genetically encoded voltage indicators

Irene Mollinedo-Gajate
, Chenchen Song
, Thomas Knöpfel^*

^*Corresponding author for this work

Department of Physics

Research output: Chapter in book/report/conference proceeding › Chapter › peer-review

16 Citations (Scopus)

Abstract

Optogenetic approaches combine the power to allocate optogenetic tools (proteins) to specific cell populations (defined genetically or functionally) and the use of light-based interfaces between biological wetware (cells and tissues) and hardware (controllers and recorders). The optogenetic toolbox contains two main compartments: tools to interfere with cellular processes and tools to monitor cellular events. Among the latter are genetically encoded voltage indicators (GEVIs). This chapter outlines the development, current state of the art and prospects of emerging optical GEVI imaging technologies.

Original language	English
Title of host publication	Optogenetics
Subtitle of host publication	Light-Sensing Proteins and Their Applications in Neuroscience and Beyond
Editors	Hiromu Yawo, Hideki Kandori, Amane Koizumi, Ryoichiro Kageyama
Publisher	Springer
Chapter	12
Pages	209-224
Number of pages	16
Edition	2nd
ISBN (Electronic)	9789811587634
ISBN (Print)	9789811587627, 9789811587658
DOIs	https://doi.org/10.1007/978-981-15-8763-4_12
Publication status	Published - 5 Jan 2021

Publication series

Name	Advances in Experimental Medicine and Biology
Volume	1293
ISSN (Print)	0065-2598
ISSN (Electronic)	2214-8019

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

User-Defined Keywords

Action potential
Brain
Fluorescent protein
Förster resonance energy transfer
Genetically encoded voltage indicators
Heart
Neuronal circuits

Access to Document

10.1007/978-981-15-8763-4_12

Cite this

Mollinedo-Gajate, I., Song, C., & Knöpfel, T. (2021). Genetically encoded voltage indicators. In H. Yawo, H. Kandori, A. Koizumi, & R. Kageyama (Eds.), Optogenetics: Light-Sensing Proteins and Their Applications in Neuroscience and Beyond (2nd ed., pp. 209-224). (Advances in Experimental Medicine and Biology; Vol. 1293). Springer. https://doi.org/10.1007/978-981-15-8763-4_12

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author = "Irene Mollinedo-Gajate and Chenchen Song and Thomas Kn{\"o}pfel",

note = "Publisher Copyright: {\textcopyright} Springer Nature Singapore Pte Ltd. 2021.",

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language = "English",

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Genetically encoded voltage indicators. / Mollinedo-Gajate, Irene; Song, Chenchen; Knöpfel, Thomas.
Optogenetics: Light-Sensing Proteins and Their Applications in Neuroscience and Beyond. ed. / Hiromu Yawo; Hideki Kandori; Amane Koizumi; Ryoichiro Kageyama. 2nd. ed. Springer, 2021. p. 209-224 (Advances in Experimental Medicine and Biology; Vol. 1293).

Research output: Chapter in book/report/conference proceeding › Chapter › peer-review

TY - CHAP

T1 - Genetically encoded voltage indicators

AU - Mollinedo-Gajate, Irene

AU - Song, Chenchen

AU - Knöpfel, Thomas

N1 - Publisher Copyright: © Springer Nature Singapore Pte Ltd. 2021.

PY - 2021/1/5

Y1 - 2021/1/5

N2 - Optogenetic approaches combine the power to allocate optogenetic tools (proteins) to specific cell populations (defined genetically or functionally) and the use of light-based interfaces between biological wetware (cells and tissues) and hardware (controllers and recorders). The optogenetic toolbox contains two main compartments: tools to interfere with cellular processes and tools to monitor cellular events. Among the latter are genetically encoded voltage indicators (GEVIs). This chapter outlines the development, current state of the art and prospects of emerging optical GEVI imaging technologies.

AB - Optogenetic approaches combine the power to allocate optogenetic tools (proteins) to specific cell populations (defined genetically or functionally) and the use of light-based interfaces between biological wetware (cells and tissues) and hardware (controllers and recorders). The optogenetic toolbox contains two main compartments: tools to interfere with cellular processes and tools to monitor cellular events. Among the latter are genetically encoded voltage indicators (GEVIs). This chapter outlines the development, current state of the art and prospects of emerging optical GEVI imaging technologies.

KW - Action potential

KW - Brain

KW - Fluorescent protein

KW - Förster resonance energy transfer

KW - Genetically encoded voltage indicators

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AN - SCOPUS:85099332157

SN - 9789811587627

SN - 9789811587658

T3 - Advances in Experimental Medicine and Biology

SP - 209

EP - 224

BT - Optogenetics

A2 - Yawo, Hiromu

A2 - Kandori, Hideki

A2 - Koizumi, Amane

A2 - Kageyama, Ryoichiro

PB - Springer

ER -

Genetically encoded voltage indicators

Abstract

Publication series

UN SDGs

User-Defined Keywords

Access to Document

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