Genetically encoded voltage indicators

Irene Mollinedo-Gajate, Chenchen Song, Thomas Knöpfel*

*Corresponding author for this work

Research output: Chapter in book/report/conference proceedingChapterpeer-review

15 Citations (Scopus)

Abstract

Optogenetic approaches combine the power to allocate optogenetic tools (proteins) to specific cell populations (defined genetically or functionally) and the use of light-based interfaces between biological wetware (cells and tissues) and hardware (controllers and recorders). The optogenetic toolbox contains two main compartments: tools to interfere with cellular processes and tools to monitor cellular events. Among the latter are genetically encoded voltage indicators (GEVIs). This chapter outlines the development, current state of the art and prospects of emerging optical GEVI imaging technologies.

Original languageEnglish
Title of host publicationOptogenetics
Subtitle of host publicationLight-Sensing Proteins and Their Applications in Neuroscience and Beyond
EditorsHiromu Yawo, Hideki Kandori, Amane Koizumi, Ryoichiro Kageyama
PublisherSpringer
Chapter12
Pages209-224
Number of pages16
Edition2nd
ISBN (Electronic)9789811587634
ISBN (Print)9789811587627, 9789811587658
DOIs
Publication statusPublished - 5 Jan 2021

Publication series

NameAdvances in Experimental Medicine and Biology
Volume1293
ISSN (Print)0065-2598
ISSN (Electronic)2214-8019

User-Defined Keywords

  • Action potential
  • Brain
  • Fluorescent protein
  • Förster resonance energy transfer
  • Genetically encoded voltage indicators
  • Heart
  • Neuronal circuits

Fingerprint

Dive into the research topics of 'Genetically encoded voltage indicators'. Together they form a unique fingerprint.

Cite this