General routes for the synthesis of mono, di and tri-N-substituted derivatives of cyclam

I. M. Helps; D. Parker; J. R. Morphy; J. Chapman

doi:10.1016/0040-4020(89)80049-3

General routes for the synthesis of mono, di and tri-N-substituted derivatives of cyclam

I. M. Helps^*
, D. Parker
, J. R. Morphy
, J. Chapman

^*Corresponding author for this work

Department of Chemistry

Research output: Contribution to journal › Journal article › peer-review

86 Citations (Scopus)

Abstract

The selective synthesis of N-substituted derivatives of 1,4,8,11-tetraazacyclotetradecane may be achieved through N-tosyl or N-benzyl intermediates, permitting for example the synthesis of 1,8 disubstituted derivatives.

Original language	English
Pages (from-to)	219-226
Number of pages	8
Journal	Tetrahedron
Volume	45
Issue number	1
DOIs	https://doi.org/10.1016/0040-4020(89)80049-3
Publication status	Published - Jan 1989

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title = "General routes for the synthesis of mono, di and tri-N-substituted derivatives of cyclam",

abstract = "The selective synthesis of N-substituted derivatives of 1,4,8,11-tetraazacyclotetradecane may be achieved through N-tosyl or N-benzyl intermediates, permitting for example the synthesis of 1,8 disubstituted derivatives.",

author = "Helps, \{I. M.\} and D. Parker and Morphy, \{J. R.\} and J. Chapman",

year = "1989",

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T1 - General routes for the synthesis of mono, di and tri-N-substituted derivatives of cyclam

AU - Helps, I. M.

AU - Parker, D.

AU - Morphy, J. R.

AU - Chapman, J.

PY - 1989/1

Y1 - 1989/1

N2 - The selective synthesis of N-substituted derivatives of 1,4,8,11-tetraazacyclotetradecane may be achieved through N-tosyl or N-benzyl intermediates, permitting for example the synthesis of 1,8 disubstituted derivatives.

AB - The selective synthesis of N-substituted derivatives of 1,4,8,11-tetraazacyclotetradecane may be achieved through N-tosyl or N-benzyl intermediates, permitting for example the synthesis of 1,8 disubstituted derivatives.

UR - https://www.scopus.com/pages/publications/0024510819

U2 - 10.1016/0040-4020(89)80049-3

DO - 10.1016/0040-4020(89)80049-3

M3 - Journal article

AN - SCOPUS:0024510819

SN - 0040-4020

VL - 45

SP - 219

EP - 226

JO - Tetrahedron

JF - Tetrahedron

IS - 1

ER -

General routes for the synthesis of mono, di and tri-N-substituted derivatives of cyclam

Abstract

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