G-quadruplexes for luminescent sensing and logic gates

Hong Zhang He; Daniel Shiu Hin Chan; Chung Hang Leung; Dik Lung Ma

doi:10.1093/nar/gkt108

G-quadruplexes for luminescent sensing and logic gates

Hong Zhang He
, Daniel Shiu Hin Chan
, Chung Hang Leung^*
, Dik Lung Ma

^*Corresponding author for this work

Department of Chemistry

Research output: Contribution to journal › Review article › peer-review

150 Citations (Scopus)

Abstract

G-quadruplexes represent a versatile sensing platform for the construction of label-free molecular detection assays owing to their diverse structures that can be selectively recognized by G-quadruplex-specific luminescent probes. In this Survey and Summary, we highlight recent examples of the application of the label-free strategy for the development of G-quadruplex-based luminescent detection platforms with a view towards the potential application of tetraplex structures in the design of DNA logic gates.

Original language	English
Pages (from-to)	4345-4359
Number of pages	15
Journal	Nucleic Acids Research
Volume	41
Issue number	8
DOIs	https://doi.org/10.1093/nar/gkt108
Publication status	Published - Apr 2013

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10.1093/nar/gkt108

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title = "G-quadruplexes for luminescent sensing and logic gates",

abstract = "G-quadruplexes represent a versatile sensing platform for the construction of label-free molecular detection assays owing to their diverse structures that can be selectively recognized by G-quadruplex-specific luminescent probes. In this Survey and Summary, we highlight recent examples of the application of the label-free strategy for the development of G-quadruplex-based luminescent detection platforms with a view towards the potential application of tetraplex structures in the design of DNA logic gates.",

author = "He, \{Hong Zhang\} and Chan, \{Daniel Shiu Hin\} and Leung, \{Chung Hang\} and Ma, \{Dik Lung\}",

note = "Funding Information: Funding for open access charge: Hong Kong Baptist University [FRG2/11-12/009]; Centre for Cancer and Inflammation Research, School of Chinese Medicine (CCIR-SCM, HKBU); the Health and Medical Research Fund [HMRF/11101212]; the Research Grants Council [HKBU/201811 and HKBU/204612]; the French National Research Agency/Research Grants Council Joint Research Scheme [A-HKBU201/12]; the Science and Technology Development Fund, Macao SAR [001/ 2012/A] and the University of Macau [MYRG091 (Y1-L2)-ICMS12-LCH and MYRG121(Y1-L2)-ICMS12-LCH].",

year = "2013",

month = apr,

doi = "10.1093/nar/gkt108",

language = "English",

volume = "41",

pages = "4345--4359",

journal = "Nucleic Acids Research",

issn = "0305-1048",

publisher = "Oxford University Press",

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TY - JOUR

T1 - G-quadruplexes for luminescent sensing and logic gates

AU - He, Hong Zhang

AU - Chan, Daniel Shiu Hin

AU - Leung, Chung Hang

AU - Ma, Dik Lung

N1 - Funding Information: Funding for open access charge: Hong Kong Baptist University [FRG2/11-12/009]; Centre for Cancer and Inflammation Research, School of Chinese Medicine (CCIR-SCM, HKBU); the Health and Medical Research Fund [HMRF/11101212]; the Research Grants Council [HKBU/201811 and HKBU/204612]; the French National Research Agency/Research Grants Council Joint Research Scheme [A-HKBU201/12]; the Science and Technology Development Fund, Macao SAR [001/ 2012/A] and the University of Macau [MYRG091 (Y1-L2)-ICMS12-LCH and MYRG121(Y1-L2)-ICMS12-LCH].

PY - 2013/4

Y1 - 2013/4

N2 - G-quadruplexes represent a versatile sensing platform for the construction of label-free molecular detection assays owing to their diverse structures that can be selectively recognized by G-quadruplex-specific luminescent probes. In this Survey and Summary, we highlight recent examples of the application of the label-free strategy for the development of G-quadruplex-based luminescent detection platforms with a view towards the potential application of tetraplex structures in the design of DNA logic gates.

AB - G-quadruplexes represent a versatile sensing platform for the construction of label-free molecular detection assays owing to their diverse structures that can be selectively recognized by G-quadruplex-specific luminescent probes. In this Survey and Summary, we highlight recent examples of the application of the label-free strategy for the development of G-quadruplex-based luminescent detection platforms with a view towards the potential application of tetraplex structures in the design of DNA logic gates.

UR - https://www.scopus.com/pages/publications/84877307520

U2 - 10.1093/nar/gkt108

DO - 10.1093/nar/gkt108

M3 - Review article

C2 - 23435319

AN - SCOPUS:84877307520

SN - 0305-1048

VL - 41

SP - 4345

EP - 4359

JO - Nucleic Acids Research

JF - Nucleic Acids Research

IS - 8

ER -

G-quadruplexes for luminescent sensing and logic gates

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