G-quadruplexes for luminescent sensing and logic gates

Hong Zhang He, Daniel Shiu Hin Chan, Chung Hang Leung*, Edmond Dik Lung MA

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

129 Citations (Scopus)

Abstract

G-quadruplexes represent a versatile sensing platform for the construction of label-free molecular detection assays owing to their diverse structures that can be selectively recognized by G-quadruplex-specific luminescent probes. In this Survey and Summary, we highlight recent examples of the application of the label-free strategy for the development of G-quadruplex-based luminescent detection platforms with a view towards the potential application of tetraplex structures in the design of DNA logic gates.

Original languageEnglish
Pages (from-to)4345-4359
Number of pages15
JournalNucleic Acids Research
Volume41
Issue number8
DOIs
Publication statusPublished - Apr 2013

Scopus Subject Areas

  • Genetics

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