G-quadruplex-based logic gates for HgII and AgI ions employing a luminescent iridium(III) complex and extension of metal-mediated base pairs by polymerase

Edmond Dik Lung MA*, Sheng Lin, Lihua Lu, Modi Wang, Chong Hu, Li Juan Liu, Kangning REN, Chung Hang Leung

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

21 Citations (Scopus)

Abstract

We report herein the synthesis of a series of cyclometallated iridium(III) complexes as luminescent G-quadruplex-selective probes, which were used to construct AND, OR and INHIBIT logic gates for the detection of HgII and AgI ions. To our knowledge, this is the first time that the C-AgI-T mismatched base pair has been used for the construction of luminescent assays or logic gates.

Original languageEnglish
Pages (from-to)4780-4785
Number of pages6
JournalJournal of Materials Chemistry B
Volume3
Issue number24
DOIs
Publication statusPublished - 28 Jun 2015

Scopus Subject Areas

  • Chemistry(all)
  • Biomedical Engineering
  • Materials Science(all)

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