From Micro to Nano Magnetic Spheres: Size-Controllable Synthesis, Multilayer Coatings, and Biomedical Applications

Ken Cham Fai Leung*, Shouhu Xuan, Yixiawg J. Wang

*Corresponding author for this work

Research output: Chapter in book/report/conference proceedingConference proceedingpeer-review


Size-controllable monodispersed ferrite microspheres to nanoparticles have been synthesized with a range of particle sizes from 10 to 1500 nm. The particle's grain size can also be tuned from 5.9 to 21.5 nm. Some of these spheres have been coated efficiently with silica, poly(aniline), dendrimer, etc., to yield well-defined core/shell-like structures. These magnetic microspheres have been functionalized successfully with organic moieties such as crown ethers, acting as a tool for the magnetic separation of discrete functional gold nanoparticles. Moreover, ultrasmall magnetic nanoparticles have been employed as both in vitro and in vivo magnetic resonance imaging contrast agents.

Original languageEnglish
Title of host publicationNanotechnology 2010
Subtitle of host publicationAdvanced Materials, CNTs, Particles, Films and Composites
PublisherCRC Press
Number of pages4
ISBN (Print)9781439834015
Publication statusPublished - 21 Jun 2010
Externally publishedYes
EventNanotechnology 2010 Conference and Expo, Nanotech 2010 - Anaheim Convention Center, Anaheim, United States
Duration: 21 Jun 201024 Jun 2010


ConferenceNanotechnology 2010 Conference and Expo, Nanotech 2010
Country/TerritoryUnited States
Internet address

Scopus Subject Areas

  • Ceramics and Composites
  • Surfaces, Coatings and Films
  • Surfaces and Interfaces

User-Defined Keywords

  • Contrast agent
  • Magnetic resonance imaging
  • Magnetite
  • Microsphere
  • Nanoparticle


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