TY - JOUR
T1 - Four New Prenylated Isoflavonoids in Tadehagi triquetrum
AU - Xiang, Wei
AU - Li, Rong Tao
AU - Mao, Yun Ling
AU - Zhang, Hong Jie
AU - Li, Sheng Hong
AU - Song, Qi Shi
AU - Sun, Han Dong
N1 - We are grateful to the Natural Science Foundation of Yunnan Province (2000C0099M) for financial support.
PY - 2005/1/1
Y1 - 2005/1/1
N2 - Investigation on the anthelminthic bioactive compounds of the ethanol extract of Tadehagi triquetrum resulted in the isolation of three new prenylated isoflavones, triquetrumones A (1), B (2), and C (3), and one new prenylated biisoflavanone, (R)-triquetrumone D (4), along with 16 known compounds, cyclokievitone (5), yukovanol (6), aromadendrin (7), kaempferol (8), astragalin (9), 2-O-methyl-L-chiro-inositol (10), galactitol (11), p-hydroxycinnamic acid (12), ursolic acid (13), betulinic acid (14), β-sitosterol (15), daucosterol (16), stigmasterol (17), stigmasta-5,22-dien-3-O-β-D- glucopyranoside (18), saccharose (19), and docosanoic acid (20). The structures of 1-4 were elucidated on the basis of spectroscopic and spectrometric methods. Compounds 1-3 displayed mild anthelminthic bioactivity, and compound 3 showed a significant binding ability to the estrogen receptor.
AB - Investigation on the anthelminthic bioactive compounds of the ethanol extract of Tadehagi triquetrum resulted in the isolation of three new prenylated isoflavones, triquetrumones A (1), B (2), and C (3), and one new prenylated biisoflavanone, (R)-triquetrumone D (4), along with 16 known compounds, cyclokievitone (5), yukovanol (6), aromadendrin (7), kaempferol (8), astragalin (9), 2-O-methyl-L-chiro-inositol (10), galactitol (11), p-hydroxycinnamic acid (12), ursolic acid (13), betulinic acid (14), β-sitosterol (15), daucosterol (16), stigmasterol (17), stigmasta-5,22-dien-3-O-β-D- glucopyranoside (18), saccharose (19), and docosanoic acid (20). The structures of 1-4 were elucidated on the basis of spectroscopic and spectrometric methods. Compounds 1-3 displayed mild anthelminthic bioactivity, and compound 3 showed a significant binding ability to the estrogen receptor.
KW - Anthelminthic
KW - Coumaronochromone
KW - Papilionaceae
KW - Tadehagi triquetrum
KW - Triquetrumones A, B, C, D
UR - http://www.scopus.com/inward/record.url?scp=12344320690&partnerID=8YFLogxK
U2 - 10.1021/jf0483117
DO - 10.1021/jf0483117
M3 - Journal article
C2 - 15656660
AN - SCOPUS:12344320690
SN - 0021-8561
VL - 53
SP - 267
EP - 271
JO - Journal of Agricultural and Food Chemistry
JF - Journal of Agricultural and Food Chemistry
IS - 2
ER -