Fluorescent properties of the amidinophenylporphyrins interacting with DNA

Kai Wang; Tian Li; Faquan Yu; Yunman Zheng; Rick W K WONG; Daniel W J KWONG; Zaoying Li

doi:10.1002/cjoc.201100564

Fluorescent properties of the amidinophenylporphyrins interacting with DNA

Kai Wang^*, Tian Li, Faquan Yu, Yunman Zheng, Rick W K WONG, Daniel W J KWONG, Zaoying Li

^*Corresponding author for this work

Department of Chemistry

Research output: Contribution to journal › Journal article › peer-review

3 Citations (Scopus)

Abstract

5,10,15,20-Tetrakis(4-amidinolphenyl)porphyrin, its Zn complex and amidinolphenyl bispophyrin interacting with calf thymus DNA were investigated by fluorescence emission spectra and fluorescence life time measurements were also shown. The binding modes of these compounds were recorded and lifetimes of luminescence were measured as a function of the nature to understand the interaction with DNA. The results suggest those amidinoporphyrins are promising new photodynamic therapeutic agents.

Original language	English
Pages (from-to)	529-533
Number of pages	5
Journal	Chinese Journal of Chemistry
Volume	30
Issue number	3
DOIs	https://doi.org/10.1002/cjoc.201100564
Publication status	Published - Mar 2012

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Chemistry(all)

User-Defined Keywords

amidinophenylporphyrin
binding mode
DNA
fluorescence
lifetime

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10.1002/cjoc.201100564

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title = "Fluorescent properties of the amidinophenylporphyrins interacting with DNA",

abstract = "5,10,15,20-Tetrakis(4-amidinolphenyl)porphyrin, its Zn complex and amidinolphenyl bispophyrin interacting with calf thymus DNA were investigated by fluorescence emission spectra and fluorescence life time measurements were also shown. The binding modes of these compounds were recorded and lifetimes of luminescence were measured as a function of the nature to understand the interaction with DNA. The results suggest those amidinoporphyrins are promising new photodynamic therapeutic agents.",

keywords = "amidinophenylporphyrin, binding mode, DNA, fluorescence, lifetime",

author = "Kai Wang and Tian Li and Faquan Yu and Yunman Zheng and WONG, {Rick W K} and KWONG, {Daniel W J} and Zaoying Li",

year = "2012",

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doi = "10.1002/cjoc.201100564",

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journal = "Chinese Journal of Chemistry",

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TY - JOUR

T1 - Fluorescent properties of the amidinophenylporphyrins interacting with DNA

AU - Wang, Kai

AU - Li, Tian

AU - Yu, Faquan

AU - Zheng, Yunman

AU - WONG, Rick W K

AU - KWONG, Daniel W J

AU - Li, Zaoying

PY - 2012/3

Y1 - 2012/3

N2 - 5,10,15,20-Tetrakis(4-amidinolphenyl)porphyrin, its Zn complex and amidinolphenyl bispophyrin interacting with calf thymus DNA were investigated by fluorescence emission spectra and fluorescence life time measurements were also shown. The binding modes of these compounds were recorded and lifetimes of luminescence were measured as a function of the nature to understand the interaction with DNA. The results suggest those amidinoporphyrins are promising new photodynamic therapeutic agents.

AB - 5,10,15,20-Tetrakis(4-amidinolphenyl)porphyrin, its Zn complex and amidinolphenyl bispophyrin interacting with calf thymus DNA were investigated by fluorescence emission spectra and fluorescence life time measurements were also shown. The binding modes of these compounds were recorded and lifetimes of luminescence were measured as a function of the nature to understand the interaction with DNA. The results suggest those amidinoporphyrins are promising new photodynamic therapeutic agents.

KW - amidinophenylporphyrin

KW - binding mode

KW - DNA

KW - fluorescence

KW - lifetime

UR - http://www.scopus.com/inward/record.url?scp=84859078179&partnerID=8YFLogxK

U2 - 10.1002/cjoc.201100564

DO - 10.1002/cjoc.201100564

M3 - Journal article

AN - SCOPUS:84859078179

SN - 1001-604X

VL - 30

SP - 529

EP - 533

JO - Chinese Journal of Chemistry

JF - Chinese Journal of Chemistry

IS - 3

ER -

Fluorescent properties of the amidinophenylporphyrins interacting with DNA

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