Five new ocotillone-type saponins from Gynostemma pentaphyllum

Xin Liu, Wencai Ye, Ziyao Mo, Biao Yu, Shouxun Zhao, Houming Wu, Chuntao Che, Renwang Jiang, Thomas C.W. Mak, Wendy W L HSIAO*

*Corresponding author for this work

Research output: Contribution to journalJournal articlepeer-review

46 Citations (Scopus)


Five new ocotillone-type saponins, gynosides A-E (1-5), along with 10 known dammarane-type saponins, were isolated from the aerial parts of Gynostemma pentaphyllum. The structures of these new compounds were determined by NMR analysis and acid hydrolysis. The structure and stereochemistry of gynoside A (1) were confirmed by X-ray crystallography.

Original languageEnglish
Pages (from-to)1147-1151
Number of pages5
JournalJournal of Natural Products
Issue number7
Publication statusPublished - Jul 2004

Scopus Subject Areas

  • Analytical Chemistry
  • Molecular Medicine
  • Pharmacology
  • Pharmaceutical Science
  • Drug Discovery
  • Complementary and alternative medicine
  • Organic Chemistry


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