Keyphrases
Protective Effect
100%
Exercise Effect
100%
3-axis
100%
Fibroblast Growth Factor 21 (FGF21)
100%
Diabetic Cardiomyopathy
100%
Mitochondrial Integrity
100%
Sirtuin 3 (SIRT3)
40%
Mitochondrial Dysfunction
30%
Knock-in Mouse Model
30%
Klotho
30%
Mitochondrial Enzymes
20%
Diabetes
20%
Exercise Benefits
20%
Forkhead Box O3 (FOXO3)
20%
Enzymatic Assay
20%
Human Induced Pluripotent Stem Cell-derived Cardiomyocytes (hiPSC-CMs)
20%
Toxic Lipids
20%
Co-receptor
10%
Oxidative Stress
10%
Phosphorylation
10%
Signaling Pathway
10%
Mitochondrial Damage
10%
Hepatocyte-specific
10%
Homeostasis
10%
Putative Drug Targets
10%
Fatty Acid Oxidation
10%
Mitochondrial Function
10%
Cardioprotection
10%
Cardiomyocytes
10%
Non-pharmacological Methods
10%
Streptozotocin
10%
High-fat Diet
10%
Wild Mice
10%
Littermate
10%
ATP Production
10%
Signaling Axis
10%
Hepatocytes
10%
Deacetylase
10%
Electron Microscopy
10%
Treadmill Exercise
10%
Exercise Intervention
10%
Adenovirus
10%
Increased Activity
10%
Functional Impairment
10%
Cardiometabolic Disease
10%
Mitochondrial Structure
10%
Cardiac Dysfunction
10%
Cardiac Function Assessment
10%
Diabetic Fibroblast
10%
Exercise Assessment
10%
Peptide Hormone
10%
Selective Ablation
10%
Hyperacetylation
10%
Mouse Cardiomyocytes
10%
Biochemistry, Genetics and Molecular Biology
FGF21
100%
Cardiac Muscle Cell
40%
SIRT3
40%
Mitochondrial Disorder
30%
Knockout Mouse
30%
Enzyme
20%
Lipid
20%
AMP-activated Protein Kinase
20%
Hepatocyte
20%
FOXO3
20%
Human Induced Pluripotent Stem Cell
20%
Oxidative Stress
10%
Wild Type
10%
Adenosine Triphosphate
10%
Homeostasis
10%
Beta Oxidation
10%
Streptozotocin
10%
Wild Type Mouse
10%
Heart Function
10%
Electron Microscopy
10%
Peptide Hormone
10%
Adeno Associated Virus
10%
Co-Receptor
10%
Pharmacology, Toxicology and Pharmaceutical Science
Fibroblast Growth Factor 21
100%
Diabetic Cardiomyopathy
100%
Knockout Mouse
30%
Mitochondrial Enzyme
20%
Receptor
20%
Fatty Acid
10%
Adenosine Triphosphate
10%
Streptozotocin
10%
Wild Type Mouse
10%
Diabetes Mellitus
10%
Electron Microscopy
10%
Peptide Hormone
10%
Functional Disease
10%
Adeno Associated Virus
10%