Fast uptake, water-soluble, mitochondria-specific erbium complex for a dual function molecular probe - Imaging and photodynamic therapy

Tao Zhang; Chi Fai Chan; Jianhua Hao; Ga Lai Law; Rick W K WONG; Ka-Leung WONG

doi:10.1039/c2ra22056c

Fast uptake, water-soluble, mitochondria-specific erbium complex for a dual function molecular probe - Imaging and photodynamic therapy

Tao Zhang, Chi Fai Chan, Jianhua Hao, Ga Lai Law^*, Rick W K WONG, Ka-Leung WONG

^*Corresponding author for this work

Department of Chemistry

Research output: Contribution to journal › Journal article › peer-review

28 Citations (Scopus)

Abstract

A water-soluble, mitochondria-permeable erbium(iii) complex has been designed as a responsive bi-functional probe. This may be used to induce the mild formation of singlet oxygen (Φ_Δ = 0.10) and causes local damage in cellulo when exposed to UV and near-infrared laser excitation.

Original language	English
Pages (from-to)	382-385
Number of pages	4
Journal	RSC Advances
Volume	3
Issue number	2
DOIs	https://doi.org/10.1039/c2ra22056c
Publication status	Published - 14 Jan 2013

Scopus Subject Areas

General Chemistry
General Chemical Engineering

Access to Document

10.1039/c2ra22056c

Cite this

@article{adcf30795c5142ac95cf272fca70b54e,

title = "Fast uptake, water-soluble, mitochondria-specific erbium complex for a dual function molecular probe - Imaging and photodynamic therapy",

abstract = "A water-soluble, mitochondria-permeable erbium(iii) complex has been designed as a responsive bi-functional probe. This may be used to induce the mild formation of singlet oxygen (ΦΔ = 0.10) and causes local damage in cellulo when exposed to UV and near-infrared laser excitation.",

author = "Tao Zhang and Chan, {Chi Fai} and Jianhua Hao and Law, {Ga Lai} and WONG, {Rick W K} and Ka-Leung WONG",

year = "2013",

month = jan,

day = "14",

doi = "10.1039/c2ra22056c",

language = "English",

volume = "3",

pages = "382--385",

journal = "RSC Advances",

issn = "2046-2069",

publisher = "Royal Society of Chemistry",

number = "2",

}

TY - JOUR

T1 - Fast uptake, water-soluble, mitochondria-specific erbium complex for a dual function molecular probe - Imaging and photodynamic therapy

AU - Zhang, Tao

AU - Chan, Chi Fai

AU - Hao, Jianhua

AU - Law, Ga Lai

AU - WONG, Rick W K

AU - WONG, Ka-Leung

PY - 2013/1/14

Y1 - 2013/1/14

N2 - A water-soluble, mitochondria-permeable erbium(iii) complex has been designed as a responsive bi-functional probe. This may be used to induce the mild formation of singlet oxygen (ΦΔ = 0.10) and causes local damage in cellulo when exposed to UV and near-infrared laser excitation.

AB - A water-soluble, mitochondria-permeable erbium(iii) complex has been designed as a responsive bi-functional probe. This may be used to induce the mild formation of singlet oxygen (ΦΔ = 0.10) and causes local damage in cellulo when exposed to UV and near-infrared laser excitation.

UR - http://www.scopus.com/inward/record.url?scp=84870941953&partnerID=8YFLogxK

U2 - 10.1039/c2ra22056c

DO - 10.1039/c2ra22056c

M3 - Journal article

AN - SCOPUS:84870941953

SN - 2046-2069

VL - 3

SP - 382

EP - 385

JO - RSC Advances

JF - RSC Advances

IS - 2

ER -

Fast uptake, water-soluble, mitochondria-specific erbium complex for a dual function molecular probe - Imaging and photodynamic therapy

Abstract

Scopus Subject Areas

Access to Document

Other files and links

Fingerprint

Cite this