Fast uptake, water-soluble, mitochondria-specific erbium complex for a dual function molecular probe - Imaging and photodynamic therapy

Tao Zhang; Chi Fai Chan; Jianhua Hao; Ga Lai Law; Rick W K WONG; Ka-Leung WONG

doi:10.1039/c2ra22056c

Fast uptake, water-soluble, mitochondria-specific erbium complex for a dual function molecular probe - Imaging and photodynamic therapy

Tao Zhang, Chi Fai Chan, Jianhua Hao, Ga Lai Law^*, Rick W K WONG, Ka-Leung WONG

^*Corresponding author for this work

Department of Chemistry

Research output: Contribution to journal › Article › peer-review

25 Citations (Scopus)

Abstract

A water-soluble, mitochondria-permeable erbium(iii) complex has been designed as a responsive bi-functional probe. This may be used to induce the mild formation of singlet oxygen (Φ_Δ = 0.10) and causes local damage in cellulo when exposed to UV and near-infrared laser excitation.

Original language	English
Pages (from-to)	382-385
Number of pages	4
Journal	RSC Advances
Volume	3
Issue number	2
DOIs	https://doi.org/10.1039/c2ra22056c
Publication status	Published - 14 Jan 2013

Scopus Subject Areas

Chemistry(all)
Chemical Engineering(all)

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abstract = "A water-soluble, mitochondria-permeable erbium(iii) complex has been designed as a responsive bi-functional probe. This may be used to induce the mild formation of singlet oxygen (ΦΔ = 0.10) and causes local damage in cellulo when exposed to UV and near-infrared laser excitation.",

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AU - Zhang, Tao

AU - Chan, Chi Fai

AU - Hao, Jianhua

AU - Law, Ga Lai

AU - WONG, Rick W K

AU - WONG, Ka-Leung

PY - 2013/1/14

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AB - A water-soluble, mitochondria-permeable erbium(iii) complex has been designed as a responsive bi-functional probe. This may be used to induce the mild formation of singlet oxygen (ΦΔ = 0.10) and causes local damage in cellulo when exposed to UV and near-infrared laser excitation.

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Fast uptake, water-soluble, mitochondria-specific erbium complex for a dual function molecular probe - Imaging and photodynamic therapy

Abstract

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