Exposure to benzophenones, parabens and triclosan among pregnant women in different trimesters

Hongzhi Zhao, Wenqian Huo, Jiufeng Li, Xinli Ma, Wei Xia, Zhengji Pang, Mingyi Xie, Shunqing Xu*, Zongwei Cai*

*Corresponding author for this work

Research output: Contribution to journalJournal articlepeer-review

33 Citations (Scopus)


Humans are potentially exposed to many environmental pollutants, many of which may cause adverse health effects, especially to pregnant women and their fetuses. In this study, 11 environmental pollutants from three different chemical classes, including benzophenones, parabens and triclosan were measured in 627 urine samples collected from 209 pregnant women to evaluate exposure and trends as a function of pregnancy stage. Methylparaben (MeP), ethylparaben, propylparaben (PrP), butylparaben, 2,4-dihydroxybenzophenone (BP-1), 2-hydroxy-4-methoxybenzophenone (BP-3) and 4-hydroxybenzophenone were detected in > 50% samples. The concentrations of BP-1 and BP-3 (Spearman's r = 0.57, p < 0.01) and those of MeP and PrP (Spearman's r = 0.68, p < 0.01) were found to be correlated. The urinary concentrations of BP-1 and BP-3 in the first trimester were significantly higher than those in the second or third trimester (Mann-Whitney U test, p < 0.05). These findings provide valuable information for improving the prediction of maternal exposure to these emerging pollutants and for assessing their potential health risks to the mother as well as the offspring.

Original languageEnglish
Pages (from-to)578-585
Number of pages8
JournalScience of the Total Environment
Publication statusPublished - 31 Dec 2017

Scopus Subject Areas

  • Environmental Engineering
  • Environmental Chemistry
  • Waste Management and Disposal
  • Pollution

User-Defined Keywords

  • Different trimesters
  • Environmental pollutants
  • Human urine samples
  • Liquid chromatography-mass spectrometry
  • Pregnant women


Dive into the research topics of 'Exposure to benzophenones, parabens and triclosan among pregnant women in different trimesters'. Together they form a unique fingerprint.

Cite this